全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Dirk Nagorsen , Peter Kufer ...
来源:[J].Pharmacology and Therapeutics(IF 7.793), 2012, Vol.136 (3), pp.334-342Elsevier
摘要:Abstract(#br)For decades, chemotherapy has been the backbone for the treatment of patients with B cell malignancies. Depending on the individual disease, monoclonal antibodies, irradiation and/or hematopoietic stem cell transplantation are added. However, the current standar...
作者:Julia Stieglmaier , Jonathan Benjamin , Dirk Nagorsen
来源:[J].Expert Opinion on Biological Therapy(IF 3.345), 2015, Vol.15 (8), pp.1093-1099Taylor & Francis
摘要:Various approaches of T-cell-based cancer immunotherapy are currently under investigation, among these are BiTE® (bispecific T-cell engager) antibody constructs, which have a unique design and mechanism of action. They are constructed by genetically linking onto a single pol...
作者:Dirk Nagorsen , Patrick A. Baeuerle
来源:[J].Experimental Cell Research(IF 3.557), 2011, Vol.317 (9), pp.1255-1260Elsevier
摘要:Abstract(#br)Severe side effects and few long-term remissions frequently limit the treatment of advanced malignant diseases. Bispecific antibodies are currently emerging as a new option for the treatment of malignant diseases, which can potentially engage all cytotoxic T cells of...
作者:Dirk Nagorsen , Francesco M Marincola , Monica C Panelli
来源:[J].Cytokine(IF 2.518), 2003, Vol.25 (1), pp.31-35Elsevier
摘要:Abstract(#br)Understanding the whole process of dendritic cell (DC) activation might help in the development of more efficient immunotherapeutic strategies for tumor patients. Part of this process is cytokine secretion, which has important effects on innate and adaptive immu...
作者:Dirk Nagorsen , Peter Kufer ...
来源:[J].2012, Vol.136 (3), pp.334-342Elsevier

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