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作者:Devika Rana , Md. Kalamuddin ...
来源:[J].Bioorganic & Medicinal Chemistry(IF 2.903), 2020, Vol.28 (1)Elsevier
摘要:Abstract(#br)Falcipains (FPs), cysteine proteases in the malarial parasite, are emerging as the promising antimalarial drug targets. In order to identify novel FP inhibitors, we generated a pharmacophore derived from the reported co-crystal structures of inhibitors of Plasmo...
作者:Devika Rana , Rajneesh Kaur ...
来源:[J].Journal of Integrated Science and Technology, 2015, Vol.3 (2), pp.39-41综合科学出版社
摘要:In the present study the synthesis of pyrazoline derivatives were carried out by cyclization of the chalchone with hydrazine hydrate in the presence of the formic acid. The synthesized pyrazoline derivatives were synthesized on the basis of prediction of activity spectra for subs...

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