全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:David M. Irwin , Weiwei Zhai
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)Springer
摘要:East Asian dog breeds are one of the most ancient groups of dogs that radiated after the domestication of the dog and represent the most basal lineages of dog evolution. Among these, the Chow Chow is an ancient breed that embodies very distinct morphological and physiological fea...
作者:Ahmad Al-Salam , David M. Irwin
来源:[J].BMC Evolutionary Biology(IF 3.285), 2017, Vol.17 (1)Springer
摘要:Insulin receptor substrate (Irs) proteins are essential for insulin signaling as they allow downstream effectors to dock with, and be activated by, the insulin receptor. A family of four Irs proteins have been identified in mice, however the gene for one of these, IRS3 , has been...
作者:... Gang Niu , David M. Irwin , Huanran Tan
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2015, Vol.16 (4), pp.7377-7393DOAJ
摘要:Glucokinase (GCK) is the rate-limiting enzyme of liver glucose metabolism. Through protein-protein interactions, glucokinase regulatory protein (GCKR) post-transcriptionally regulates GCK function in the liver, and causes its nuclear localization. However the role of GCK in regul...
作者:David M. Irwin , Gang Niu
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2015, Vol.16 (6), pp.11966-11982DOAJ
摘要:Tumor-associated macrophages (TAMs) have been found to be associated with the progression and metastasis of breast cancer. To clarify the mechanisms underlying the crosstalk between TAMs and cancer stem cells (CSCs) in breast cancer recurrence and metastasis, we used a co-cu...
作者:David M. Irwin , Yongyi Shen
来源:[J].Mitochondrion(IF 4.025), 2014, Vol.18, pp.70-75Elsevier
摘要:Abstract(#br)Galliform birds inhabit very diverse habitats, including plateaus that are above 3000 m in altitude. At high altitude, lower temperature and hypoxia are two important factors influencing survival. Mitochondria, as the ultimate oxygen transductor, play an important ro...
作者:David M. Irwin , Huanran Tan
来源:[J].Molecular Phylogenetics and Evolution(IF 4.066), 2014, Vol.70, pp.195-203Elsevier
摘要:Abstract(#br)Glucose is an essential nutrient that must be distributed throughout the body to provide energy to sustain physiological functions. Glucose is delivered to distant tissues via be blood stream, and complex systems have evolved to maintain the levels of glucose within ...

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