全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Darja Karpova , Susanne Bräuninger ...
来源:[J].Journal of Translational Medicine(IF 3.459), 2017, Vol.15 (1)Springer
摘要:Certain disadvantages of the standard hematopoietic stem and progenitor cell (HSPC) mobilizing agent G-CSF fuel the quest for alternatives. We herein report results of a Phase I dose escalation trial comparing mobilization with a peptidic CXCR4 antagonist POL6326 (balixafortide) ...
作者:Darja Karpova , Kavi Devraj ...
来源:[J].PLoS Biology(IF 11.452), 2014, Vol.12 (6)DOAJ
摘要:Mechanisms behind how the immune system signals to the brain in response to systemic inflammation are not fully understood. Transgenic mice expressing Cre recombinase specifically in the hematopoietic lineage in a Cre reporter background display recombination and marker gene expr...
作者:Darja Karpova , Milica Bunos ...
来源:[J].Cytotherapy(IF 3.055), 2015, Vol.17 (10), pp.1465-1471Elsevier
摘要:Abstract(#br)Background aims(#br)Immunomagnetic enrichment of CD34+ hematopoietic “stem” cells (HSCs) using paramagnetic nanobead coupled CD34 antibody and immunomagnetic extraction with the CliniMACS plus system is the standard approach to generating T-cell-depleted stem ce...
作者:Darja Karpova , Thomas Lehrnbecher ...
来源:[J].Cytotherapy(IF 3.055), 2015, Vol.17 (10), pp.1396-1405Elsevier
摘要:Abstract(#br)Background aims(#br)Evidence of the criticality of the adaptive immune response for controlling invasive aspergillosis has been provided. This observation is supported by the fact that invasive aspergillosis, a grave complication of allogeneic stem cell transpla...
作者:Darja Karpova , Reinhold Kerb ...
来源:[J].Human Mutation(IF 5.213), 2012, Vol.33 (4), pp.750-762Wiley
摘要:Abstract(#br)The multidrug resistance‐associated protein 2 (MRP2/ABCC2) is involved in the efflux of endogenous and xenobiotic substrates, including several anticancer and antiviral drugs. The functional consequences of ABCC2 protein variants remain inconsistent, which may b...
作者:Darja Karpova , Halvard Bonig
来源:[J].STEM CELLS(IF 7.701), 2015, Vol.33 (8), pp.2391-2399Wiley
摘要:Abstract(#br)Dominant, although nonexclusive roles of CXCR4 and its chief ligand CXCL12 in bone marrow (BM) retention and preservation of the relative quiescence of hematopoietic stem/progenitor cells (HSPCs), along with their involvement in human immunodeficiency virus infe...

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