全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Damien Chaussabel , Jacques Banchereau ...
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.13 (1)DOAJ
摘要:Globally, diarrheal diseases are a leading cause of death in children under five and disproportionately affect children in developing countries. Children who contract diarrheal diseases are rarely screened to identify the etiologic agent due to time and cost considerations associ...
作者:... Laurent Chiche , Charlie Quinn , Damien Chaussabel
来源:[J].Journal of Translational Medicine(IF 3.459), 2015, Vol.13 (1)Springer
摘要:Abstract(#br) Background(#br)Systems immunology approaches have proven invaluable in translational research settings. The current rate at which large-scale datasets are generated presents unique challenges and opportunities. Mining aggregates of these datasets could accelera...
作者:... Jacques Banchereau , Damien Chaussabel , Octavio Ramilo
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (4)DOAJ
摘要:Staphylococcus aureus infections are associated with diverse clinical manifestations leading to significant morbidity and mortality. To define the role of the host response in the clinical manifestations of the disease, we characterized whole blood transcriptional profiles of chi...
作者:Damien Chaussabel , Ronan Breen ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (10)DOAJ
摘要:Mycobacterium tuberculosis infection is a leading cause of infectious death worldwide. Gene-expression microarray studies profiling the blood transcriptional response of tuberculosis (TB) patients have been undertaken in order to better understand the host immune response as well...
作者:Damien Chaussabel , Uma Malhotra
来源:[J].PLoS Pathogens(IF 9.127), 2016, Vol.12 (1)DOAJ
摘要:Most West Nile virus (WNV) infections are asymptomatic, but some lead to neuroinvasive disease with symptoms ranging from disorientation to paralysis and death. Evidence from animal models suggests that neuroinvasive infections may arise as a consequence of impaired immune p...
作者:... Jacques Banchereau , Damien Chaussabel , Octavio Ramilo
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (5)DOAJ
摘要:Staphylococcus aureus has emerged as a significant pathogen causing severe invasive disease in otherwise healthy people. Despite considerable advances in understanding the epidemiology, resistance mechanisms, and virulence factors produced by the bacteria, there is limited knowle...
作者:... Jacques Banchereau , Damien Chaussabel , Anne O'Garra
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.11 (2)DOAJ
摘要:Analysis of the mouse transcriptional response to Listeria monocytogenes infection reveals that a large set of genes are perturbed in both blood and tissue and that these transcriptional responses are enriched for pathways of the immune response. Further we identified enrich...
作者:... Jacques Banchereau , Damien Chaussabel , Octavio Ramilo
来源:[J].PLoS Medicine(IF 16.269), 2013, Vol.10 (11)DOAJ
摘要:Respiratory syncytial virus (RSV) is the leading cause of viral lower respiratory tract infection (LRTI) and hospitalization in infants. Mostly because of the incomplete understanding of the disease pathogenesis, there is no licensed vaccine, and treatment remains symptomatic. We...

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