全部文献期刊会议图书|学者科研项目
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作者:... Lijie Guo , Hongsheng Bi , Dadong Guo
来源:[J].International Immunopharmacology(IF 2.417), 2020, Vol.79
摘要:Abstract(#br)Uveitis is the most common cause in inflammatory eye diseases that can lead to visual impairment even blindness worldwide. T helper (Th) 17 and regulatory T (Treg) cells are critical mediators for immune response. Notch signaling can regulate the cell differenti...
作者:Dadong Guo , Zhe Wang ...
来源:[J].Archives of Biochemistry and Biophysics(IF 3.37), 2020, Vol.683
摘要:Abstract(#br)Glaucoma is the leading cause of irreversible blindness in the world and trabeculectomy remains still the most commonly performed filtration surgery. Failure of trabeculectomy is due to the formation of scarring, which is associated with the increased fibroblast...
作者:Dadong Guo , Meihua Ding ...
来源:[J].BMC Genomics(IF 4.397), 2020, Vol.21 (3), pp.e1005432-25
摘要:Abstract(#br)Background(#br)Myopia is one of the most common vision defects worldwide. microRNAs can regulate the target gene expression, influencing the development of diseases. Results(#br)To investigate the alterations of microRNA profiling in negative lens-induced myopia (NLI...
作者:Dadong Guo , Jianfeng Wu ...
来源:[J].Steroids(IF 2.803), 2018, Vol.139, pp.1-9
摘要:Abstract(#br)Glucocorticoid (GC) has been widely used in clinic. However, the effect of GC on normal and myopic development of eyes is still unknown. In this study, 3-week-old guinea pigs were randomly divided into four groups: No-Lens (control), GC+No-Lens, negative lens-in...
作者:... Chen Chen , Hongsheng Bi , Dadong Guo
来源:[J].Archives of Biochemistry and Biophysics(IF 3.37), 2019, Vol.669, pp.1-10
摘要:Abstract(#br)Glaucoma is a major cause of irreversible blindness in the world and filtering surgery is commonly carried out to control intraocular pressure. Failure of filtering surgery is usually due to postoperative scarring, and fibroblast proliferation, collagen producti...
作者:... Wenjun Jiang , Hongsheng Bi , Dadong Guo
来源:[J].Journal of Inorganic Biochemistry(IF 3.197), 2018, Vol.187, pp.25-32
摘要:Abstract(#br)Zinc (Zn) is a fundamental trace element for cell viability and physiology, and concentrations above the physiological level may lead to cell damage. In order to explore the effect of zinc chloride (ZnCl 2 ) on murine photoreceptor cells, in this study, we investigat...
作者:Dadong Guo , Peiming Gu ...
来源:[J].Journal of Chromatography B(IF 2.487), 2015, Vol.976-977, pp.84-90
摘要:Abstract(#br)Uveitis is a severe autoimmune eye disease that can cause intraocular inflammation even lead to severe vision loss, and the occurrence of uveitis can be closely associated with abnormal expression of proteins. However, the abnormally expressed proteins involved ...
作者:Dadong Guo , Yuanyuan Guo ...
来源:[J].European Journal of Pharmacology(IF 2.592), 2016, Vol.777, pp.33-40
摘要:Abstract(#br)As an anti-microtubule agent, paclitaxel has been widely applied clinically. However, the effects of paclitaxel on human tenon's fibroblast (HTF) proliferation and migration in vitro was still unclear. In the present study, we explored the influences of paclitax...
作者:Dadong Guo , Weikang Bi ...
来源:[J].Frontiers in Pharmacology, 2016, Vol.7
摘要:Carbon monoxide (CO) poisoning is one of the most important health concerns and may result in neuropathologic changes and neurologic sequelae. However, few studies have addressed the correlation between CO poisoning and blood-brain barrier (BBB) impairment. In this study, we inve...
作者:Dadong Guo , Yuxiang Du ...
来源:[J].Archives of Biochemistry and Biophysics(IF 3.37), 2014, Vol.560, pp.44-51
摘要:Abstract(#br)Zinc (Zn), the second abundant trace element in living organisms, plays an important role in regulating cell metabolism, signaling, proliferation, gene expression and apoptosis. Meanwhile, the overload of Zn will disrupt the intracellular calcium homeostasis via...

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