全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Haesol Lee , Dahae Lee ...
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2018, Vol.19 (3)DOAJ
摘要:Cisplatin is a well-known anticancer drug frequently used for treating solid tumors, including ovarian, testicular, bladder, and cervical tumors. However, usage of cisplatin has been limited because of its adverse effects, particularly nephrotoxicity. Therefore, the present study...
作者:Seulah Lee , Dahae Lee ...
来源:[J].Molecules(IF 2.428), 2017, Vol.22 (10)DOAJ
摘要:The edible fungus Phellinus baumii Pilat (Hymenochaetaceae) has been used in Korean traditional medicines for strengthening health and prolonging life. An extract of the fruiting bodies of P. baumii was subjected to bioassay-guided fractionation based on its anti-inflammator...
作者:Dahae Lee , Hyuk-Jai Jang ...
来源:[J].Evidence-Based Complementary and Alternative Medicine(IF 1.722), 2015, Vol.2015Hindawi
摘要:The present study investigated the renoprotective effect of an Artemisia asiatica extract and eupatilin in kidney epithelial (LLC-PK1) cells. Although cisplatin is effective against several cancers, its use is limited due to severe nephrotoxicity. Eupatilin is a flavonoid compoun...
作者:Dahae Lee , Taejung Kim ...
来源:[J].Evidence-Based Complementary and Alternative Medicine(IF 1.722), 2016, Vol.2016Hindawi
摘要:Ginsenosides are the active components of Panax ginseng . Many research studies indicate that these deglycosylated, less-polar ginsenosides have better bioactivity than the major ginsenosides. In the present study, we sought to verify the enhanced anticancer effect of P. ginseng ...
作者:Dahae Lee , Pilju Choi ...
来源:[J].Bioorganic Chemistry(IF 1.732), 2019, Vol.90Elsevier
摘要:Abstract(#br)We evaluated the protective effects of hypoxylonol C and 4,5,4′,5′-tetrahydroxy-1,1′-binaphthyl (BNT) isolated from Annulohypoxylon annulatum on pancreatic β-cell apoptosis, using the β-cell toxin streptozotocin (STZ). Hypoxylonol C and BNT restored the STZ...
作者:Dahae Lee , Seulah Lee ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2017Elsevier
摘要:Abstract(#br)Cisplatin-induced nephrotoxicity is a serious adverse effect that limits the use of cisplatin in cancer patients. In the present study, we investigated the protective effect of lanostane triterpenoids ( 1 – 10 ) isolated from the ethanolic extract of Poria cocos...
作者:Dahae Lee , Taejung Kim ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2017, Vol.27 (14), pp.3156-3161Elsevier
摘要:Abstract(#br)Guggulsterone derivatives were prepared using [3+2] click chemistry with aryl and alkyl acetylene. The series of derivatives were evaluated for their cellular protective effects on cisplatin-treated cultured LLC-PK1 kidney epithelial cells. Among the guggulsterone-tr...
作者:Dahae Lee , Dong-Soo Lee ...
来源:[J].Journal of Ginseng Research(IF 2.259), 2018, Vol.42 (1), pp.75-80Elsevier
摘要:Abstract(#br)Background(#br)The aim of the present study was to evaluate the potential protective effects of six ginsenosides (Rb1, Rb2, Rc, Rd, Rg1, and Rg3) isolated from Panax ginseng against tacrolimus (FK506)-induced apoptosis in renal proximal tubular LLC-PK1 cells.(#b...
作者:Tae Kyoung Lee , Dahae Lee ...
来源:[J].Bioorganic Chemistry(IF 1.732), 2019, Vol.87, pp.117-122Elsevier
摘要:Abstract(#br)Curcuma zedoaria rhizome (Zingiberaceae) is a well-known traditional medicinal plant used in Ayurvedic and traditional Chinese medicine to treat various cancers. This study aimed to identify the cytotoxic components from C. zedoaria rhizomes that act against gas...

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