全部文献期刊会议图书|学者科研项目
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作者:Sérgio E. D. Dias , Ana Mafalda Martins ...
来源:[J].BMC Bioinformatics(IF 3.024), 2017, Vol.18 (1)
摘要:Protein cavities play a key role in biomolecular recognition and function, particularly in protein-ligand interactions, as usual in drug discovery and design. Grid-based cavity detection methods aim at finding cavities as aggregates of grid nodes outside the molecule, under the c...
作者:S. D. C. Mendes , M. Ramírez-Castrillón ...
来源:[J].World Journal of Microbiology and Biotechnology(IF 1.262), 2017, Vol.33 (6)
摘要:Yeasts were isolated from three vineyards located in the South Region of Brazil. A cross evaluation was carried out at the oldest vineyard of the study in Pinheiro Preto. Samples of grape berries, grapevine leaves and the soil, along with samples of the winery equipment and ...
作者:Vir D. Patel , John A. Capra
来源:[J].BMC Genomics(IF 4.397), 2017, Vol.18 (1)
摘要:microRNAs (miRNAs) are essential to the regulation of gene expression in eukaryotes, and improper expression of miRNAs contributes to hundreds of diseases. Despite the essential functions of miRNAs, the evolutionary dynamics of how they are integrated into existing gene regulator...
作者:Dale D. Tang , Brennan D. Gerlach
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Smooth muscle cell migration has been implicated in the development of respiratory and cardiovascular systems; and airway/vascular remodeling. Cell migration is a polarized cellular process involving a protrusive cell front and a retracting trailing rear. There are three cytoskel...
作者:Miguel D. Campos , D. Cogollo ...
来源:[J].Journal of High Energy Physics, 2017, Vol.2017 (8)
摘要:We propose several Two Higgs Doublet Models with the addition of an Abelian gauge group which free the usual framework from flavor changing neutral interactions and explain neutrino masses through the seesaw mechanism. We discuss the kinetic and mass-mixing gripping phenomenology...
作者:Florencia D. Rojas , Mariana S. Fernández ...
来源:[J].Mycopathologia(IF 1.489), 2017, Vol.182 (11-12), pp.1119-1123
摘要:A case of cavitary pulmonary sporotrichosis without mucocutaneous involvement caused by Sporothrix schenckii is reported in a sexagenarian woman with a long smoking history. The patient was hospitalized for septic shock with multiorgan failure from a respiratory focus. The diagno...
作者:D. Verdi , C. J. Múnez ...
来源:[J].The International Journal of Advanced Manufacturing Technology(IF 1.205), 2017, Vol.92 (5-8), pp.3033-3042
摘要:Ni-based superalloys, like Inconel 625, are commonly used in different industrial sectors, like aerospace and power generation. The performance of Inconel 625 could be improved by the addition of ceramic particles like Cr3C2. The high costs involved usi...
作者:Robert D. Bongard , Michael Lepley ...
来源:[J].BMC Biochemistry(IF 1.776), 2017, Vol.18 (1)
摘要:Protein tyrosine phosphatases (PTPs) like dual specificity phosphatase 5 (DUSP5) and protein tyrosine phosphatase 1B (PTP1B) are drug targets for diseases that include cancer, diabetes, and vascular disorders such as hemangiomas. The PTPs are also known to be notoriously difficul...
作者:Cort D. Lawton , Bennet A. Butler ...
来源:[J].Journal of Orthopaedic Surgery and Research(IF 1.013), 2017, Vol.12 (1)
摘要:The surgical treatment of end-stage tibiotalar arthritis continues to be a controversial topic. Advances in surgical technique and implant design have lead to improved outcomes after both ankle arthrodesis (AA) and total ankle arthroplasty (TAA), yet a clear consensus regarding t...

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