全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Cynthia St. Hilaire , Luis Hortells ...
来源:[J].Cellular and Molecular Bioengineering(IF 1.443), 2017, Vol.10 (5), pp.483-500Springer
摘要:Lack of effective pharmacological treatment makes valvular calcification a significant clinical problem in patients with valvular disease and bioprosthetic/mechanical valve replacement therapies. Elevated levels of reactive oxygen species (ROS) in valve tissue have been identifie...
作者:Cynthia St. Hilaire , Milka Koupenova ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2008, Vol.375 (3), pp.292-296Elsevier
摘要:Abstract(#br)Proliferation of vascular smooth muscle cells (VSMC), oxidative stress, and elevated inflammatory cytokines are some of the components that contribute to plaque formation in the vasculature. The cytokine tumor necrosis factor-alpha (TNF-α) is released during vas...
作者:Cynthia St. Hilaire , Heidi Dorward ...
来源:[J].Molecular Genetics and Metabolism(IF 2.834), 2011, Vol.103 (1), pp.44-50Elsevier
摘要:Abstract(#br)Arterial Calcification due to Deficiency of CD73 (ACDC) results from mutations in the NT5E gene encoding the 5′ exonucleotidase, CD73. We now describe the third familial case of ACDC, including radiological and histopathological details of the arterial calcifica...
作者:Cynthia St. Hilaire , Wai-Man Chan ...
来源:[J].The American Journal of Human Genetics(IF 11.202), 2002, Vol.71 (5), pp.1195-1199Elsevier
摘要:Duane syndrome is a congenital eye movement disorder characterized most typically by absence of abduction, restricted adduction, and retraction of the globe on attempted adduction. Duane syndrome can be coinherited with radial ray anomalies as an autosomal dominant trait, re...
作者:Cynthia St. Hilaire , Ying Guo ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2008, Vol.366 (1), pp.156-161Elsevier
摘要:Abstract(#br)Lysyl oxidase is required for the normal biosynthesis and maturation of collagen and elastin. It is expressed by vascular smooth muscle cells, and its increased expression has been previously found in atherosclerosis and in models of balloon angioplasty. The lys...
作者:Cynthia St. Hilaire , Barbara M. Schreiber ...
来源:[J].Experimental Cell Research(IF 3.557), 2004, Vol.305 (2), pp.277-291Elsevier
摘要:Abstract(#br)Vascular smooth muscle cell polyploidization occurs during normal development and is enhanced under physiologic stress, but the mechanism of this cell cycle has not been explored. We show via time-lapse video imaging and immunofluorescence analyses that primary vascu...
作者:Cynthia St. Hilaire , Ronald A. DePinho ...
来源:[J].Aging Cell(IF 5.705), 2007, Vol.6 (2), pp.257-260Wiley
摘要:Summary(#br)We previously reported that the frequency of polyploid aortic vascular smooth muscle cells (VSMC) serves as a biomarker of aging. Cellular senescence of somatic cells is another marker of aging that is characterized by the inability to undergo cell division. Here...

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