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作者:... Di Luigi L , Lenzi A , Crescioli C
来源:[J].Endocrine, 2018, Vol.59 (3), pp.602-613
摘要:PURPOSE(#br)Tadalafil seems to ameliorate insulin resistance and glucose homeostasis in humans. We have previously reported that tadalafil targets human skeletal muscle cells with an insulin (I)-like effect. We aim to evaluate in human fetal skeletal muscle cells after tadal...
作者:Crescioli C , Villari D ...
来源:[J].Molecular and cellular endocrinology(IF 4.039), 2002, Vol.198 (1-2), pp.69-75
摘要:Prostate growth and differentiation is under the control of androgens not only during fetal life and childhood but also in adulthood, and it has been proposed that increased prostatic concentration of androgens, or increased androgen responsiveness, causes benign prostatic hyperp...
作者:Crescioli C , Mancina R ...
来源:[J].Molecular and cellular endocrinology(IF 4.039), 2002, Vol.193 (1-2), pp.89-100
摘要:Oxytocin (OT) is a neurohypophysial hormone with unclear physiological functions in the male. Several previous studies indicated that OT might have a role in the ejaculatory process, stimulating sperm release from the epididymal storage. In this study we investigated on the prese...
作者:Crescioli C , Maggi M ...
来源:[J].The Journal of clinical endocrinology and metabolism(IF 6.43), 2003, Vol.88 (4), pp.1815-24
摘要:It is generally assumed that male genital development is determined by androgens on a default program leading to female genitalia. Female genitalia virilization is due to high levels of androgens, whereas feminization is linked to reduction or lack of fetal androgen. Excess andro...
作者:Crescioli C , Ferruzzi P ...
来源:[J].Endocrinology(IF 4.717), 2003, Vol.144 (7), pp.3046-57
摘要:We have recently found that analog V (BXL-353, a calcitriol analog) inhibits growth factor (GF)-stimulated human benign prostate hyperplasia (BPH) cell proliferation by disrupting signal transduction, reducing Bcl-2 expression, and inducing apoptosis. We now report that BXL-353 b...
作者:Crescioli C , Maggie M ...
来源:[J].The Journal of clinical endocrinology and metabolism(IF 6.43), 2000, Vol.85 (7), pp.2576-83
摘要:Prostate enlargement and function is under the dual control of androgens and intraprostatic growth factors. They regulate, in concert, prostate cell proliferation and apoptosis. An increased signaling of both growth factors and androgens are supposed to underlie benign prostate h...
作者:Crescioli C , Granchi S ...
来源:[J].Molecular human reproduction(IF 4.542), 2003, Vol.9 (12), pp.765-74
摘要:The penis remains in a hypo-oxygenated, flaccid state for a large majority of the time. In this study, we investigated the effect of changing oxygen tension on the expression and functional activity of endothelin-1 (ET-1) receptors in the penis. Experiments were performed in rabb...
作者:Crescioli C , Ferruzzi P ...
来源:[J].Molecular human reproduction(IF 4.542), 2002, Vol.8 (12), pp.1053-64
摘要:We report for the first time that penile smooth muscle cells (SMC) not only respond to, but also synthesize, endothelin-1 (ET-1), one of the main regulators of SMC activity. Immunohistochemical studies indicated that, beside endothelial cells (EC), SMC of the human adult and feta...

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