全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Constantinos Giaginis , Christos Damaskos ...
来源:[J].BMC Gastroenterology(IF 2.11), 2015, Vol.15 (1)Springer
摘要:Abstract(#br) Background(#br)Histone deacetylases (HDACs) have been associated with malignant tumor development and progression in humans. HDAC inhibitors (HDACIs) are currently being explored as anti-cancer agents in clinical trials. The present study aimed to evaluate the ...
作者:Constantinos Giaginis , Despoina Spyropoulou ...
来源:[J].BMC Cancer(IF 3.333), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)Primary invasive Extramammary Paget’s vulvar disease is a rare tumor that is challenging to control. Wide surgical excision represents the standard treatment approach for Primary invasive Extramammary Paget’s vulvar disease. The goal of the curre...
作者:... Abhay T. Sangamwar , Shyam S. Sharma , Constantinos Giaginis
来源:[J].PPAR Research(IF 2.685), 2014, Vol.2014Hindawi
摘要:Parkinson’s disease (PD) is a common neurodegenerative disorder affecting 1% of the population by the age of 65 years and 4-5% of the population by the age of 85 years. PD affects functional capabilities of the patient by producing motor symptoms and nonmotor symptoms. Apart...
作者:... Ursel Soomets , Anton Terasmaa , Constantinos Giaginis
来源:[J].PPAR Research(IF 2.685), 2014, Vol.2014Hindawi
摘要:Valproic acid (VPA) is a widely used anticonvulsant and mood-stabilizing drug whose use is often associated with drug-induced weight gain. Treatment with VPA has been shown to upregulate Wfs1 expression in vitro . Aim of the present study was to compare the effect of chronic VPA ...
作者:... Carlos Ueira-Vieira , Luiz Ricardo Goulart , Constantinos Giaginis
来源:[J].PPAR Research(IF 2.685), 2016, Vol.2016Hindawi
摘要:The cyclopentenone prostaglandin 15-deoxy-Δ12,14-prostaglandin J2 (15d-PGJ2) is a natural ligand of peroxisome proliferator-activated receptor gamma (PPAR- γ ) and a potential mediator of apoptosis in cancer cells. In the present study, we ev...
作者:... Jian Yang , Meena Kishore Sakharkar , Constantinos Giaginis
来源:[J].PPAR Research(IF 2.685), 2017, Vol.2017Hindawi
摘要:Peroxisome proliferator-activated receptor gamma (PPAR γ ) is a potential target for the treatment of several disorders. In view of several FDA approved kinase inhibitors, in the current study, we have investigated the interaction of selected kinase inhibitors with PPAR γ us...
作者:... Hussein Shoaito , Thierry Fournier , Constantinos Giaginis
来源:[J].PPAR Research(IF 2.685), 2017, Vol.2017Hindawi
摘要:The peroxisome-proliferator-activated-receptor- γ (PPAR γ ) is a member of the nuclear receptor superfamily that plays a critical role in diverse biological processes, including adipogenesis, lipid metabolism, and placental development. To study the activity of PPAR γ , we c...
作者:Constantinos Giaginis , Anastasia Sampani ...
来源:[J].Pathology & Oncology Research(IF 1.555), 2018, Vol.24 (3), pp.631-640Springer
摘要:Abstract(#br)Hu-antigen R (HuR), a RNA-binding protein, is considered to play a crucial role in tumor development and progression by stabilizing or regulating a group of cellular mRNAs of cancer-related genes, such as cyclooxygenase-2 (COX-2). The present study aimed to eval...
作者:... Antonios Koutelidakis , Stamatios Theocharis , Constantinos Giaginis
来源:[J].Nutrition and Cancer(IF 2.695), 2017, Vol.69 (8), pp.1151-1176Taylor & Francis
摘要:ABSTRACT(#br)Malnutrition is a common finding in cancer patients, which can affect disease progression and survival. This review aims to critically summarize the prognostic role of nutritional status, from Body Mass Index (BMI) and weight loss to nutrition screening tools and bio...
作者:Constantinos Giaginis , Eugene Dana ...
来源:[J].Journal of Oral and Maxillofacial Surgery(IF 1.333), 2016Elsevier
摘要:Purpose(#br)Phosphorylated epidermal growth factor receptor (pEGFR) activates several signaling pathways, resulting in tumor-promoting cellular activities, and has been implicated in malignant transformation and disease progression. The present study evaluated the clinical signif...

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