全部文献期刊会议图书|学者科研项目
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作者:Claudia Hube-Magg , Georgia Makrypidi-Fraune ...
来源:[J].Gynecologic Oncology(IF 3.929), 2020, Vol.156 (3), pp.669-675
摘要:Abstract(#br)Objective(#br)Mismatch repair (MMR) deficiency and Bethesda panel microsatellite instability (MSI) are increasingly analyzed to identify tumors that might benefit from immune checkpoint inhibitors, but tumor heterogeneity is a potential obstacle for such analyses. In...
作者:Claudia Hube-Magg , Christina Möller-Koop ...
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2020, Vol.38 (2), pp.43.e13-43.e20
摘要:Abstract(#br)Background and methods(#br)8p deletions are common in renal cell carcinoma. To study their prognostic impact and association with kidney cancer phenotype, a tissue microarray with 1,809 cancers was analyzed by fluorescence in situ hybridization for 8p21 copy numbers....
作者:Claudia Hube-Magg , Christina Möller-Koop ...
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2018
摘要:Abstract(#br)Objective(#br)Antibodies against carbonic anhydrase IX (CAIX) are often part of immunohistochemical panels used to assist renal cell cancer (RCC) subtyping. This study was undertaken to determine, whether assessing CAIX expression levels could provide additional...
作者:Claudia Hube-Magg , Andreas M Luebke ...
来源:[J].Neoplasia, 2019, Vol.21 (9), pp.872-881
摘要:Abstract(#br)Dysregulation of S100A8 is described in many different human tumor types, but its role in prostate cancer is unknown. To evaluate the clinical relevance of S100A8 expression in prostate cancer, a tissue microarray containing 13,665 tumors was analyzed by immunohistoc...
作者:Claudia Hube-Magg , Martina Kluth ...
来源:[J].Neoplasia, 2017, Vol.19 (9), pp.707-715
摘要:Abstract(#br)Biglycan (BGN), a proteoglycan of the extracellular matrix, is included in mRNA signatures for prostate cancer aggressiveness. To understand the impact of BGN on prognosis and its relationship to molecularly defined subsets, we analyzed BGN expression by immunohistoc...
作者:Claudia Hube-Magg , Martina Kluth ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2018, Vol.105 (1), pp.50-56
摘要:Abstract(#br)HSD3B2 plays a crucial role in steroid hormone biosynthesis and is thus of particular interest in hormone dependent tumors such as prostate cancer. To clarify the clinical relevance of HSD3B2 expression in prostate cancer, we analyzed HSD3B2 protein expression by imm...
作者:Claudia Hube-Magg , Georgia Makrypidi-Fraune ...
来源:[J].Urologic Oncology: Seminars and Original Investigations(IF 3.647), 2019
摘要:Abstract(#br)Background(#br)Microsatellite instability (MSI), a hypermutator phenotype described in many cancers, has emerged as a predictive biomarker for immune checkpoint inhibitor therapy. Cancer heterogeneity represents a potential obstacle for the analysis of prediciti...
作者:Claudia Hube-Magg , Martina Kluth ...
来源:[J].Neoplasia, 2017, Vol.19 (4), pp.279-287
摘要:Abstract(#br)The A Disintegrin and Metalloproteinase (ADAM) family of endopeptidases plays a role in many solid cancers and includes promising targets for anticancer therapies. Deregulation of ADAM15 has been linked to tumor aggressiveness and cell line studies suggest that ADAM1...
作者:Claudia Hube-Magg , Sarah Minner ...
来源:[J].Human Pathology(IF 2.843), 2015, Vol.46 (4), pp.514-523
摘要:Summary(#br)The cytosolic factor Saccharomyces cerevisiae –like 1 (SEC14L1) is a regulator of lipid metabolism and signaling pathways that has been suggested to play a role in cancer. To learn more about its relevance for prostate cancer, SEC14L1 expression was analyzed on a...
作者:Claudia Hube-Magg , Sarah Minner ...
来源:[J].Experimental and Molecular Pathology(IF 2.128), 2015, Vol.98 (3), pp.419-426
摘要:Abstract(#br)Histone deacetylases (HDACs) play an important role in tumor development and progression by modifying histone and non-histone proteins. In the current study we analyzed prevalence and prognostic impact of HDAC1 in prostate cancer. HDAC1 expression was analyzed by imm...

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