全部文献期刊会议图书|学者科研项目
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作者:Chunyan Lei , Ru Lin ...
来源:[J].Inflammation Research(IF 1.964), 2017, Vol.66 (6), pp.523-534Springer
摘要:To investigate whether activation of the liver X receptors (LXRs) inhibits amyloid β1–40 (Aβ1–40) induced inflammatory and senescent responses in human retinal pigment epithelial (RPE) cells.
作者:Chunyan Lei , Jiaming Wang
来源:[J].Journal of Neuroinflammation(IF 4.351), 2016, Vol.13 (1)Springer
摘要:Abstract(#br) Background(#br)Retinal inflammation is a devastating pathological process in ocular diseases. Functional impairment of retinal pigment epithelium (RPE) is associated with inflammatory retinal diseases. Enhancing the protective axis namely ACE2/Ang-(1-7)/Mas by ...
作者:Chunyan Lei , Qionghua Deng ...
来源:[J].Journal of Stroke and Cerebrovascular Diseases(IF 1.984), 2019, Vol.28 (9), pp.2376-2387Elsevier
摘要:Abstract(#br)Background and Purpose: Silent brain infarct (SBI), which has traditionally been considered clinically silent, has been proposed as a subclinical risk marker for future cognitive function decline. Methods: We conducted a systematic review of literature in the Co...
作者:Chunyan Lei , Ru Lin ...
来源:[J].Neuroscience(IF 3.122), 2017, Vol.360, pp.48-60Elsevier
摘要:Abstract(#br)Amyloid β (Aβ) is a pathogenic peptide associated with many neurodegenerative diseases such as Alzheimer’s disease and Parkinson's disease. The retinal inflammation in response to Aβ is implicated in the pathogenesis of several ocular diseases including age...
作者:Chunyan Lei , Tao Chen ...
来源:[J].World Neurosurgery(IF 1.765), 2018, Vol.111, pp.47-54Elsevier
摘要:Background(#br)The association between pre–intracerebral hemorrhage (ICH) statin use and clinical outcomes after intracerebral hemorrhage (ICH) is still conflicting. Recently, some studies investigating the effects of in-hospital statin use after the onset of ICH have been p...
作者:Chunyan Lei , Jia Geng ...
来源:[J].Journal of Stroke and Cerebrovascular Diseases(IF 1.984), 2018, Vol.27 (6), pp.1705-1710Elsevier
摘要:Background(#br)Hematoma growth is a strong independent predictor of poor outcome after intracerebral hemorrhage. However, there is no gold standard to accurately predict hematoma growth. Several noncontrast computed tomographic markers associated with hematoma growth have been re...
作者:Chunyan Lei , Yao Xiong ...
来源:[J].Journal of Stroke and Cerebrovascular Diseases(IF 1.984), 2017, Vol.26 (1), pp.230-236Elsevier
摘要:Background(#br)Identifying the etiology of ischemic stroke is essential to acute management and secondary prevention. The value of liver function indicators in differentiating stroke subtypes remains to be evaluated.(#br)Methods(#br)A total of 1333 acute ischemic stroke patients ...
作者:Chunyan Lei , Junfeng Liu ...
来源:[J].World Neurosurgery(IF 1.765), 2019, Vol.129, pp.e669-e676Elsevier
摘要:Background(#br)Results are conflicting as to whether sex has an impact on the outcome of intracerebral hemorrhage (ICH), especially when etiologies differ. In this study, we investigated whether sex differences exist in patients with vascular abnormality−related ICH.(#br)Met...
作者:Chunyan Lei , Bo Wu ...
来源:[J].Journal of Clinical Neuroscience(IF 1.253), 2015, Vol.22 (3), pp.498-503Elsevier
摘要:Abstract(#br)Individuals with diabetes are at a higher risk of suffering stroke, but whether chronic hyperglycemia affects clinical outcomes after stroke is unclear. We examined whether chronic hyperglycemia, measured in terms of hemoglobin A 1C (HbA 1C ) levels, influences ...
作者:Chunyan Lei , Bo Wu ...
来源:[J].Brain Research(IF 2.879), 2016, Vol.1632, pp.1-8Elsevier
摘要:Abstract(#br)Activation of the immune system via toll-like receptor 4 (TLR4) is implicated in both negative and positive processes in the central nervous system, including inflammation and angiogenesis. Whether TLR4 also participates in brain recovery following intracerebral hemo...

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