全部文献期刊会议图书|学者科研项目
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作者:... Xian Xue , Jianzhong Li , Chunsun Dai
来源:[J].Cellular Signalling(IF 4.304), 2019, Vol.62
摘要:Abstract(#br)Upon occurrence of kidney injury, tubular cells arrested in G2/M stage may promote interstitial fibroblast activation and kidney fibrosis through producing large amounts of pro-fibrotic cytokines. MTORC1 signaling is essential for controlling cell growth, however, th...
作者:... Weichun He , Junwei Yang , Chunsun Dai
来源:[J].Cellular Signalling(IF 4.304), 2018, Vol.46, pp.43-51
摘要:Abstract(#br)Lupus nephritis (LN) is a chronic autoimmune disorder. Here we try to identify the candidate genes in macrophages related to LN. We performed a systematic search in the Gene Expression Omnibus (GEO) database for microarray in human mononuclear cells and mouse macroph...
作者:... Weichun He , Junwei Yang , Chunsun Dai
来源:[J].Cellular Signalling(IF 4.304), 2018, Vol.42, pp.249-258
摘要:Abstract(#br)The CD38, possessing ADP-ribosyl cyclase (ADPR-cyclase) and cyclic ADP-ribose hydrolase (cADPR-hydrolase), is able to regulate a variety of cellular activities. However, the role and mechanisms for CD38 in macrophage activation and sepsis-induced acute kidney in...
作者:... Xiaochun Wu , Chunsun Dai , Junwei Yang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)
摘要:Although a large number of drugs have been used to treat chronic hepatitis C (CHC), there still remains a great challenge to treat maintenance hemodialysis (MHD) patients with chronic hepatitis C. To clarify the immunnoloregulation of double filtration plasmapheresis (DFPP) in MH...
作者:... Yafang Yang , Chunsun Dai , Junwei Yang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (10)
摘要:BACKGROUND: MicroRNAs (miRNAs) are small ribonucleotides regulating gene expression. MicroRNAs are present in the blood in a remarkably stable form and have emerged as potential diagnostic markers in patients with cardiovascular disease. Our study aimed to assess circulating miR-...
作者:... Weichun He , Chunsun Dai , Junwei Yang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (12)
摘要:Chronic inflammation is highly prevalent in maintenance hemodialysis (MHD) patients, and it has been shown to be a strong predictor of morbidity and mortality. Mitochondrial DNA (mtDNA) released into circulation after cell damage can promote inflammation in patients and anim...
作者:... Weichun He , Chunsun Dai , Junwei Yang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (6)
摘要:Inflammation is a pathologic feature of hyperuricemia in clinical settings. However, the underlying mechanism remains unknown. Here, infiltration of T cells and macrophages were significantly increased in hyperuricemia mice kidneys. This infiltration of inflammatory cells wa...
作者:Chunsun Dai , Junwei Yang
来源:[J].Experimental Cell Research(IF 3.557), 2016, Vol.345 (2), pp.206-217
摘要:Abstract(#br)Arterial medial calcification (AMC) is prevalent in patients with chronic kidney disease (CKD) and contributes to elevated risk of cardiovascular events and mortality. Vascular smooth muscle cells (VSMCs) to osteogenic transdifferentiation (VOT) in a high-phosph...
作者:... Jiafa Ren , Yifan Dai , Chunsun Dai
来源:[J].Scientific Reports(IF 2.927), 2017, Vol.7 (1)
摘要:Scientific Reports 7: Article number: 46146; published online: 10 April 2017; updated: 26 June 2017. This Article contains an error in Figure 6B, where the first sample of wt mouse for p-Akt (Thr308) should have been omitted. The correct Figure 6 appears below as Figure 1.
作者:... Jiafa Ren , Yifan Dai , Chunsun Dai
来源:[J].Scientific Reports(IF 2.927), 2017, Vol.7 (1), pp.915-27
摘要:Abstract(#br)Epidemiologic studies showed the correlation between the deficiency of omega-3 polyunsaturated fatty acids (n-3 PUFAs) and the progression of chronic kidney diseases (CKD), however, the role and mechanisms for n-3 PUFAs in protecting against kidney fibrosis rema...

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