全部文献期刊会议图书|学者科研项目
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作者:Chunhui Wu , Yu Wang ...
来源:[J].Neurobiology of Learning and Memory(IF 3.327), 2020, Vol.167
摘要:Abstract(#br)Clinical and preclinical researches have shown that sub-anesthetic ketamine elicits sustained antidepressant effects for up to 1–2 weeks. Pharmacokinetics studies (t1/2 = 23 min) in mice showed no ketamine residue at 24 h after sub-anesthetic or anesthetic ketam...
作者:Chunhui Wu , Feipu Yang ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2020, Vol.30 (8)
摘要:Abstract(#br)A series of triazolopyridinone derivatives originating from the antidepressant trazodone was designed and pharmacologically evaluated. Most of the compounds with a multireceptor functional profile exhibited high potency at the D 2 , 5-HT 1A , and 5-HT 2A receptors. C...
作者:... Hong Yang , Chunhui Wu , Yiyao Liu
来源:[J].Acta Biomaterialia(IF 5.093), 2019, Vol.89, pp.1-13
摘要:Abstract(#br)Recently, drug delivery systems based on nanotechnology have received great attention in cancer therapeutics and diagnostics since they can not only improve the treatment efficacy but also reduce the side effects. Among them, mesoporous silica nanoparticles (MSNs) wi...
作者:Chunhui Wu , Ningtin Huang ...
来源:[J].Free Radical Biology and Medicine(IF 5.271), 2018, Vol.124, pp.163-175
摘要:Abstract(#br)Acute lung injury (ALI) and its more severe form acute respiratory distress syndrome (ARDS) are life-threatening conditions with high morbility and mortality, underscoring the urgent need for novel treatments. Leaves of the medicinal herb Microcos paniculata hav...
作者:Chunhui Wu , Zhen Wang ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2018, Vol.145, pp.74-85
摘要:Abstract(#br)In the present study, a series of multi-target N-substituted cyclic imide derivatives which possessed potent dopamine D 2 , serotonin 5-HT 1A and 5-HT 2A receptors properties were synthesized and evaluated as potential antipsychotics. Among these compounds, (3aR...
作者:Chunhui Wu , Junqing Guo ...
来源:[J].Optics Communications(IF 1.438), 2015, Vol.354, pp.107-111
摘要:Abstract(#br)In this paper, a 682 Mbit/s phosphorescent white LED visible light communication (VLC) system utilizing 16-quadrature-amplitude-modulation orthogonal frequency division multiplexing (16QAM-OFDM) modulation based on analog equalizers without blue filter is firstl...
作者:Chunhui Wu , Qian Huang ...
来源:[J].Journal of Controlled Release(IF 7.633), 2015, Vol.202, pp.40-48
摘要:Abstract(#br)Cyclopamine (CPA), a potent inhibitor of the Hedgehog pathway, has produced promising anticancer results in a number of preclinical studies. CPA has also been found to enhance tumor response to radiation therapy. However, CPA is water insoluble. A drug delivery ...

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