全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Yali Hou , Chung-I Wu , Jue Ruan
来源:[J].BMC Genomics(IF 4.397), 2016, Vol.17 (1)Springer
摘要:Abstract(#br) Background(#br)NGS (next generation sequencing) has been widely used in studies of biological processes, ranging from microbial evolution to cancer genomics. However, the error rate of NGS (0.1 % ~ 1 %) is still remaining a great challenge for comprehensively invest...
作者:... Xuemei Lu , Yong E. Zhang , Chung-I Wu
来源:[J].BMC Genomics(IF 4.397), 2018, Vol.19 (1), pp.1-12DOAJ
摘要:Abstract Background A gene regulatory network (GRN) comprises many weak links that are often regulated by microRNAs. Since miRNAs rarely repress their target genes by more than 30%, doubts have been expressed about the biological relevance of such weak effects. These doubts ...
作者:... Yixin Zhao , Zhongqi Liufu , Chung-I Wu
来源:[J].BMC Genomics(IF 4.397), 2018, Vol.19 (1), pp.1-8DOAJ
摘要:Abstract Background New genes are constantly formed, sometimes from non-genic sequences, creating what is referred to as de novo genes. Since the total number of genes remains relatively steady, gene deaths likely balance out new births. In metazoan genomes, microRNAs (miRs)...
作者:Chung-I Wu , Wu-Shiun Hsieh
来源:[J].PLoS ONE(IF 3.73), 2018, Vol.7 (10)DOAJ
摘要:Understanding the genetic basis of the physical and behavioral traits that separate humans from other primates is a challenging but intriguing topic. The adaptive functions of the expansion and/or reduction in human brain size have long been explored. From a brain transcriptome p...
作者:Xuemei Lu , Chung-I Wu
来源:[J].BMC Biology(IF 6.531), 2011, Vol.9 (1)Springer
摘要:Abstract(#br)The X chromosome has fewer testis-specific genes than autosomes in many species. This bias is commonly attributed to X inactivation in spermatogenesis but a recent paper in BMC Biology provides evidence against X inactivation in Drosophila and proposes that somatic t...

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