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作者:Chrystian Junqueira Alves , Jessica Ruivo Maximino , Gerson eChadi
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2015, Vol.9
摘要:Schwann cells are the main source of paracrine support to motor neurons. Oxidative stress and mitochondrial dysfunction have been correlated to motor neuron death in Amyotrophic Lateral Sclerosis (ALS). Despite the involvement of Schwann cells in early neuromuscular disruption in...
作者:Chrystian Junqueira Alves , Luana Pereira de Santana ...
来源:[J].Brain Research(IF 2.879), 2011, Vol.1394, pp.90-104
摘要:Abstract(#br)Amyotrophic lateral sclerosis (ALS) is a progressive degenerative disorder affecting motoneurons and the SOD1 G93A transgenic mice are widely employed to study disease physiopathology and therapeutic strategies. Despite the cellular and biochemical evidences of an ea...
作者:Gabriela Pintar Oliveira , Chrystian Junqueira Alves , Gerson eChadi
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2013, Vol.7
摘要:Amyotrophic Lateral Sclerosis (ALS) is an adult-onset and fast progression neurodegenerative disease that leads to the loss of motor neurons. Mechanisms of selective motor neuron loss in ALS are unknown. The early events occurring in the spinal cord that may contribute to motor n...
作者:... Gabriela Pintar de Oliveira , Chrystian Junqueira Alves , Gerson eChadi
来源:[J].Frontiers in Cellular Neuroscience(IF 4.469), 2014, Vol.8
摘要:Early molecular events related to cytoskeleton are poorly described in Amyotrophic Lateral Sclerosis (ALS), especially in the Schwann cell (SC), which offers strong trophic support to motor neurons. DAVID tool identified cytoskeleton-related genes by employing the Cellular Compon...
作者:Marília Sena de Felipe , Chrystian Junqueira Alves , Rogerio Estevam Farias
来源:[J].Jornal Brasileiro de Patologia e Medicina Laboratorial, 2010, Vol.46 (1), pp.41-45
摘要:O linfoma B intravascular de grandes células (IVLBCL) é uma doença rara caracterizada pela proliferação neoplásica de células linfoides no interior de capilares. Relatamos um caso de IVLBCL em paciente jovem do sexo feminino com comprometimento bilateral da glândula sup...

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