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作者:Christy R. Hagan , Andrea R. Daniel ...
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2012, Vol.357 (1-2), pp.43-49
摘要:Abstract(#br)Progesterone receptors (PR), in concert with peptide growth factor-initiated signaling pathways, initiate massive expansion of the epithelial cell compartment associated with the process of alveologenesis in the developing mammary gland. PR-dependent signaling e...
作者:Christy R. Hagan , Emily J. Faivre , Carol A. Lange
来源:[J].Steroids(IF 2.803), 2008, Vol.74 (7), pp.568-572
摘要:Abstract(#br)Progesterone is an ovarian steroid hormone that is essential for normal breast development. The actions of progesterone are largely mediated through binding to its cognate steroid hormone receptor, the progesterone receptor (PR). PR isoforms exist in the nucleus and ...
作者:Gloria M. Trinca , Christy R. Hagan
来源:[J].Journal of Bioenergetics and Biomembranes(IF 1.604), 2018, Vol.50 (3), pp.199-204
摘要:Abstract(#br)O-GlcNAcylation is emerging as a critical regulatory post-translational modification, impacting proteins that regulate cell division, apoptosis, metabolism, cell signaling, and transcription. O-GlcNAc also affects biological homeostasis by integrating information com...
作者:Christy R. Hagan , Charles M. Rudin
来源:[J].Genes, Chromosomes and Cancer(IF 3.546), 2007, Vol.46 (3), pp.248-260
摘要:Abstract(#br)Among the cellular responses observed following treatment with DNA‐damaging agents is the activation of Short Interspersed Elements (SINEs; retrotransposable genetic elements that comprise over 10% of the human genome). By placing a human SINE (the Alu element) ...
作者:Christy R. Hagan , Charles M. Rudin
来源:[J].American Journal of Pharmacogenomics, 2002, Vol.2 (1), pp.25-35
摘要:Abstract(#br)Approximately one-quarter of the human genome is composed of short and long interspersed elements (SINEs and LINEs, respectively). These elements have spread throughout the genome by a process termed retrotransposition, consisting of transcription of an element ...

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