全部文献期刊会议图书|学者科研项目
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作者:Christoph Engel , Katharina Pfeifer ...
来源:[J].Archives of Gynecology and Obstetrics(IF 1.33), 2017, Vol.296 (6), pp.1135-1144
摘要:The aim of this analysis in a pilot study population was to investigate whether we can verify seemingly harmful lifestyle factors such as nicotine and alcohol indulgence, obesity, and physical inactivity, as well as a low socioeconomic status for increased cancer prevalence in a ...
作者:Christoph Engel , Claudia Matthäus-Krämer ...
来源:[J].Intensive Care Medicine(IF 5.258), 2017, Vol.43 (11), pp.1602-1612
摘要:Guidelines recommend administering antibiotics within 1 h of sepsis recognition but this recommendation remains untested by randomized trials. This trial was set up to investigate whether survival is improved by reducing the time before initiation of antimicrobial therapy by mean...
作者:Christoph Engel , Walter Vetter ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)
摘要:Health benefits of the Mediterranean Diet (MD) have been shown in different at-risk populations. A German translation of the Mediterranean Diet Adherence Screener (MEDAS) from the PREvención con DIeta MEDiterránea (PREDIMED) consortium was used in the LIBRE study, investigat...
作者:... Martin Halle , Stephan C. Bischoff , Christoph Engel
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)
摘要:Women with pathogenic BRCA germline mutations have an increased risk for breast and ovarian cancer that seems to be modified by life-style factors. Though, randomized trials investigating the impact of lifestyle interventions on cancer prevention and prognosis in BRCA carriers ar...
作者:Christoph Engel , Klaus Heine
来源:[J].Public Choice, 2017, Vol.173 (1-2), pp.217-240
摘要:In a nutshell, price cap regulation is meant to establish a quid pro quo: regulators are obliged by law to intervene only at rare, previously defined points in time, and only by imposing an upper bound on prices; firms are meant to justify regulatory restraint by adopting sociall...
作者:Christoph Engel , Aysel Ahadova ...
来源:[J].Gastroenterology(IF 12.821), 2020, Vol.158 (5), pp.1326-1333
摘要:Background & Aims(#br)Lynch syndrome is caused by variants in DNA mismatch repair (MMR) genes and associated with an increased risk of colorectal cancer (CRC). In patients with Lynch syndrome, CRCs can develop via different pathways. We studied associations between Lynch syn...
作者:Christoph Engel , Markus Loeffler
来源:[J].Ophthalmology(IF 5.563), 2020, Vol.127 (3), pp.357-368
摘要:Purpose(#br)To investigate the role of sex on retinal nerve fiber layer (RNFL) thickness at 768 circumpapillary locations based on OCT findings.(#br)Design(#br)Population-based cross-sectional study.(#br)Participants(#br)We investigated 5646 eyes of 5646 healthy participants...
作者:Christoph Engel , Cornelia Enzenbach ...
来源:[J].Journal of Occupational Medicine and Toxicology, 2020, Vol.15 (1), pp.1
摘要:Psychosocial stressors in the workplace can be detrimental to mental health. Conflicts at work, e.g. aggression, hostility or threats from coworkers, supervisors or customers, can be considered a psychosocial stressor, possibly increasing risk for depressive symptoms. Existi...
作者:Christoph Engel , Tobias Gubbey ...
来源:[J].Cell(IF 31.957), 2017, Vol.169 (1), pp.120-131.e22
摘要:Summary(#br)Transcription initiation at the ribosomal RNA promoter requires RNA polymerase (Pol) I and the initiation factors Rrn3 and core factor (CF). Here, we combine X-ray crystallography and cryo-electron microscopy (cryo-EM) to obtain a molecular model for basal Pol I ...
作者:Christoph Engel , Hans F. Vasen ...
来源:[J].Gastroenterology(IF 12.821), 2018
摘要:Abstract(#br)Background & Aims(#br)Patients with Lynch syndrome are at high risk for developing colorectal cancer (CRC). Regular colonoscopic surveillance is recommended, but there is no international consensus on the appropriate interval. We investigated whether shorter int...

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