全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Chiho Matsuda , Mitsutoshi Yoneyama ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2012, Vol.428 (4), pp.494-499Elsevier
摘要:Abstract(#br)Interferon regulatory factor-3 (IRF-3), a key transcriptional factor in the type I interferon system, is frequently impaired by hepatitis C virus (HCV), in order to establish persistent infection. However, the exact mechanism by which the virus establishes persi...
作者:Chiho Matsuda , Yukiko Hayashi ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2006, Vol.346 (1), pp.67-73Elsevier
摘要:Abstract(#br)Serine palmitoyltransferase (SPT) is a first-step enzyme in the sphingolipid biosynthetic pathway. Myriocin is an inhibitor of SPT and suppresses replication of the hepatitis C virus (HCV) replicon. However, it is still unknown whether this SPT inhibitor suppres...
作者:Chiho Matsuda , Shusuke Kuge ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2006, Vol.353 (4), pp.882-888Elsevier
摘要:Abstract(#br)Persistent infection with hepatitis C virus (HCV) is a major cause of liver diseases such as chronic hepatitis, liver cirrhosis, and hepatocellular carcinoma. Here we report that inhibition of heat shock protein 90 (Hsp90) is highly effective in suppressing HCV genom...
作者:Chiho Matsuda , Toshiyuki Tanaka ...
来源:[J].Journal of Medical Virology(IF 2.373), 2010, Vol.82 (9), pp.1545-1553Wiley
摘要:Abstract(#br)The mechanism of the innate immune response to hepatitis C virus (HCV) has not been fully elucidated, largely due to the lack of an appropriate model. We used HCV transgenic (Tg) mice, which express core, E1, E2, and NS2 proteins regulated by the Cre/ loxP switc...
作者:Chiho Matsuda , Michinori Kohara ...
来源:[J].Bioconjugate Chemistry(IF 4.58), 2010, Vol.22 (1), pp.42-49ACS
摘要:The small italic letters represent 2′-deoxyribonucleosides. ... The organic layer was washed with aqueous NaHCO3 (saturated) and brine, dried (Na2SO4), and concentrated. ...

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