全部文献期刊会议图书|学者科研项目
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作者:Chien-Heng Shen , Te-Sheng Chang ...
来源:[J].Journal of the Formosan Medical Association(IF 1), 2020, Vol.119 (1), pp.532-537
摘要:Background/Purpose(#br)The major dose-limiting toxicity of ribavirin is hemolytic anemia. We investigated the incidence, risk factors and impact on virological response of anemia in chronic hepatitis C genotype 2 patients receiving sofosbuvir plus ribavirin therapy.(#br)Methods(#...
作者:Chien-Heng Shen , Shui-Yi Tung
来源:[J].Journal of Functional Foods(IF 2.632), 2016, Vol.21, pp.474-484
摘要:Abstract(#br)Hericium erinaceus is a well-known edible mushroom with valuable biological properties. Erinacine A is the major active agent of the diterpenoid compounds of the cultured mycelia of H. erinaceus. This agent has multiple physiological activities, including anti-t...
作者:Chien-Heng Shen , Shui-Yi Tung ...
来源:[J].Toxicology(IF 4.017), 2014, Vol.316, pp.61-70
摘要:Abstract(#br)Tert-butyl hydroperoxide (t-BHP), an organic lipid hydroperoxide analog, has been demonstrated to exert pro-oxidant effects to evaluate mechanisms involving oxidative stress in hepatocyte cells and rat liver. Herein, we present an investigation of the event of m...
作者:... Chien-Te Lee , Chien-Heng Shen , Tsung-Hui Hu
来源:[J].American Journal of Kidney Diseases(IF 5.294), 2013, Vol.62 (4), pp.789-795
摘要:Background(#br)Pegylated interferon (peginterferon; interferon with an attached polyethylene glycol molecule) monotherapy is the recommended treatment for chronic hepatitis C virus (HCV) infection in hemodialysis patients. Limited data concerning peginterferon alfa-2b and ri...
作者:Chien-Heng Shen , Yung-Yu Hsieh ...
来源:[J].Cellular Physiology and Biochemistry(IF 3.415), 2018, Vol.51 (6), pp.2616-2630
摘要:Background/Aims: Colorectal cancer (CRC) is the third most common type of cancer and the second leading cause of cancer-related deaths worldwide. PRDXs are antioxidant enzymes that play an important role in cell differentiation, proliferation and apoptosis and have diverse f...
作者:Chien-Heng Shen , Chung-Chi Huang ...
来源:[J].Nutrients(IF 2.072), 2019, Vol.11 (9)
摘要:Malnutrition is associated with adverse outcomes in patients with liver cirrhosis. Relevant data about nutrition risk in critically ill cirrhotic patients are lacking. The modified Nutrition Risk in Critically Ill (mNUTRIC) score is a novel nutrition risk assessment tool spe...
作者:Chien-Heng Shen , Shui-Yi Tung
来源:[J].PLOS ONE(IF 3.73), 2017, Vol.12 (1)
摘要:CIL-102 (1-[4-(furo[2,3-b]quinolin-4-ylamino)phenyl]ethanone) is a well-known, major active agent of the alkaloid derivative of Camptotheca acuminata with valuable biological properties, including anti-tumorigenic activity. In this study, we investigated the molecular mechan...
作者:Chien-Heng Shen , Yung-Yu Hsieh ...
来源:[J].PLOS ONE(IF 3.73), 2016, Vol.11 (9)
摘要:The stromal cell–derived factor-1 (SDF-1)/CXC receptor 4 (CXCR4) axis plays an important role in tumor angiogenesis and invasiveness in colorectal cancer (CRC) progression. In addition, metastatic CRC remains one of the most difficult human malignancies to treat because of i...
作者:Chien-Heng Shen , Meng-Chiao Hsieh ...
来源:[J].IJMS(IF 2.464), 2014, Vol.15 (9), pp.15073-15089
摘要:Hericium erinaceus , an edible mushroom, has been demonstrated to potentiate the effects of numerous biological activities. The aim of this study was to investigate whether H . erinaceus mycelium could act as an anti-inflammatory agent to bring about neuroprotection using a ...
作者:Chien-Heng Shen , Meng Chiao Hsieh ...
来源:[J].Antioxidants, 2020, Vol.9 (2)
摘要:Hericium erinaceus, a valuable pharmaceutical and edible mushroom, contains potent bioactive compounds such as H. erinaceus mycelium (HEM) and its derived ethanol extraction of erinacine A, which have been found to regulate physiological functions in our previous study. Howe...

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