全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Changrun Guo , Gang Ding ...
来源:[J].Drug Design, Development and Therapy(IF 3.486), 2016, Vol.2016 (default), pp.799-810Dove
摘要:Background: Diabetic nephropathy has become the most common cause of morbidity and mortality in diabetic patients. Therefore, there is an urgent need for more effective and safer drugs for use in this condition. Purpose: The aims of this study were to investigate the amelior...
作者:Changrun Guo , Sha Liao ...
来源:[J].Molecules(IF 2.428), 2012, Vol.17 (11), pp.12868-12881DOAJ
摘要:Diabetic retinopathy is a complex disease that potentially involves increased production of advanced glycosylation end products (AGEs) and elevated aldose reductase (AR) activity, which are related with oxidative stress and inflammation. The aim of this study was to investigate t...
作者:... Cheng Ji , Weihong Ge , Changrun Guo
来源:[J].European Journal of Nutrition(IF 3.127), 2019, Vol.58 (7), pp.2713-2729Springer
摘要:Abstract(#br) Purpose(#br)Fatalities due to heart and cerebrovascular diseases caused by uncontrolled hyperlipidaemia increase every year; on the other hand, lipid-lowering drugs are known to cause side effects. The gut microbiota has been thoroughly investigated by research...
作者:Changrun Guo , Jinyang Shen ...
来源:[J].Phytomedicine(IF 2.972), 2016, Vol.23 (2), pp.149-155Elsevier
摘要:Abstract(#br)Background(#br)Polygala tenuifolia Willd is a Traditional Chinese Medicine used for the treatment of learning and memory deficits. Triterpenoid saponins, the main bioactive compounds of Polygala tenuifolia Willd, are easily hydrolyzed to polygalacic acid (PA).(#br)Pu...
作者:Changrun Guo , Chunfeng Zhang ...
来源:[J].Phytomedicine(IF 2.972), 2014, Vol.21 (6), pp.807-814Elsevier
摘要:Abstract(#br)Oxymatrine, a quinolizidine alkaloid, has been widely used for the treatment of hepatitis. In this study, we investigated the hypoglycemic and hypolipidemic effects and new pharmacological activities of oxymatrine, in a high-fat diet and streptozotocin (STZ)-induced ...
作者:Changrun Guo , Lu Li ...
来源:[J].Environmental Toxicology and Pharmacology(IF 2.005), 2014, Vol.37 (1), pp.37-44Elsevier
摘要:Abstract(#br)This study was designed to investigate the action of timosaponin B-II, a main bioactive compound in Anemarrhena asphodeloides Bunge, on the prevention from high glucose-induced cytotoxicity and apoptosis in human umbilical vein endothelial cells (HUVECs) and the pote...
作者:Changrun Guo , Chongzhi Wang
来源:[J].Fitoterapia(IF 2.231), 2016, Vol.110, pp.116-122Elsevier
摘要:Abstract(#br)Emodin is an active anthraquinone derivative from Rheum palmatum and some other Chinese herbs and it is traditionally used for treating a variety of diseases. In this study, we investigated the hypocholesterolemic effects and mechanism of emodin on hypercholeste...
作者:Changrun Guo , Liping Wang
来源:[J].Journal of Luminescence(IF 2.144), 2014, Vol.145, pp.74-80Elsevier
摘要:Abstract(#br)Due to the unique optical and chemical features of quantum dots and the special structural advantages of carbon nanohorns, it is highly desirable to synthesize nanohorns/quantum dots nanocompsite which can be applied in cell labeling and in vivo imaging. Here, we rep...
作者:... Xiaolin Yang , Zhaoqing Meng , Changrun Guo
来源:[J].Phytomedicine(IF 2.972), 2016, Vol.23 (12), pp.1504-1510Elsevier
摘要:Abstract(#br)Background(#br)High dietary fructose can cause metabolic syndrome and renal injury.(#br)Purpose(#br)The effects of protodioscin on metabolic syndrome and renal injury were investigated in mice receiving high-dose fructose.(#br)Methods(#br)Mice received 30% (w/v)...
作者:Changrun Guo , Chuanzhi Liu ...
来源:[J].Chemical Research in Chinese Universities(IF 0.735), 2014, Vol.30 (6), pp.959-964Springer
摘要:Abstract(#br)In this work, we synthesized the polypyrrole(PPy) modified gold nanoparticles and demonstrated their negligible cytotoxicity in vitro . These nanoparticles have also been demonstrated to efficiently ablate different kinds of tumor cells in vitro under the irradiation...

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