全部文献期刊会议图书|学者科研项目
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作者:Carsten Denkert , Hermann Wiebringhaus ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2017, Vol.163 (3), pp.495-506
摘要:The GeparSepto study demonstrated that the use of nab-paclitaxel instead of paclitaxel prior to anthracycline-based chemotherapy could lead to a significantly increased pCR rate, especially in the triple negative subpopulation. We report efficacy and safety for patients treated w...
作者:Carsten Denkert , Balázs Győrffy ...
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)
摘要:Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients emphasizing the need for powerful biomarkers that ...
作者:... Alexander Baur , Carsten Denkert , Berit Pfitzner
来源:[J].Annals of Diagnostic Pathology(IF 0.975), 2020, Vol.44
摘要:Abstract(#br)Desmoid-type fibromatoses (or desmoid tumors) are entities of intermediate biological potential and are locally invasive. Radical surgery, as state of the art therapy, is frequently limited by incomplete resections. Hormone modifying therapies are promising but ...
作者:Carsten Denkert , Hans Tesch ...
来源:[J].European Journal of Cancer(IF 5.061), 2020, Vol.130, pp.92-101
摘要:Abstract(#br)Aim(#br)This pooled analysis aimed to evaluate locoregional recurrence (LRR) rates of breast cancer (BC) after neoadjuvant chemotherapy (NACT) and to identify independent LRR predictors.(#br)Methods(#br)10,075 women with primary BC from nine neoadjuvant trials w...
作者:Carsten Denkert , Knut Engels ...
来源:[J].European Journal of Cancer(IF 5.061), 2017, Vol.84, pp.1-8
摘要:Abstract(#br)Background(#br)The GENEVIEVE study compared the pathological complete response (pCR) rate (ypT0/is ypN0/+) in patients with operable human epidermal growth factor receptor 2 (HER2)–negative breast cancer (BC) treated with either cabazitaxel or paclitaxel.(#br)Me...
作者:Carsten Denkert , Sylvia Adams ...
来源:[J].Seminars in Cancer Biology(IF 7.436), 2017
摘要:Abstract(#br)Morphological evaluation of tumor-infiltrating lymphocytes (TILs) in breast cancer is gaining momentum as evidence strengthens the clinical relevance of this immunological biomarker. TILs in the post-neoadjuvant residual disease setting are acquiring increasing impor...
作者:Carsten Denkert , Jeffrey S. Ross
来源:[J].The Breast(IF 2.491), 2019, Vol.44, pp.29-32
摘要:Abstract(#br)Metaplastic breast cancer (MPBC) is a rare subtype that accounts for <1% of all breast cancers. Although these are typically “triple negative,” they are relatively chemotherapy-refractory compared to conventional triple negative invasive breast cancers with more...
作者:Carsten Denkert , Hagen Kulbe ...
来源:[J].Neoplasia, 2018, Vol.20 (3), pp.280-288
摘要:Abstract(#br)PURPOSE: Tumor-infiltrating lymphocytes (TILs) have an established impact on the prognosis of high-grade serous ovarian carcinoma (HGSOC), however, their role in recurrent ovarian cancer is largely unknown. We therefore systematically investigated TIL densities and M...
作者:Giancarlo Pruneri , Andrea Vingiani , Carsten Denkert
来源:[J].The Breast(IF 2.491), 2018, Vol.37, pp.207-214
摘要:Abstract(#br)Immunoediting represents a complex and dynamic process involving cancer and immune system cells, composed by three intertwined phases: elimination, equilibrium and escape. A large number of immune cell subtypes are involved, each playing a peculiar role in interactin...

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