全部文献期刊会议图书|学者科研项目
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作者:Carol A. Sartorius , Tianjie Shen , Kathryn B. Horwitz
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2003, Vol.79 (3), pp.287-299Springer
摘要:Abstract(#br)Sixty to seventy percent of all primary human breast cancers are estrogen-dependent and express both estrogen (ER) and progesterone receptors (PR). Whereas expression of the two naturally occurring PR isoforms, PR-A and PR-B, is close to equimolar in normal huma...
作者:... J. Chuck Harrell , Anthony Elias , Carol A. Sartorius
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2012, Vol.135 (2), pp.415-432Springer
摘要:Abstract(#br)Bypassing estrogen receptor (ER) signaling during development of endocrine resistance remains the most common cause of disease progression and mortality in breast cancer patients. To date, the majority of molecular research on ER action in breast cancer has occu...
作者:... Anthony Elias , Kathryn B. Horwitz , Carol A. Sartorius
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2011, Vol.128 (1), pp.45-55Springer
摘要:Abstract(#br)A majority of breast cancers are estrogen receptor (ER) positive and have a luminal epithelial phenotype. However, these ER+ tumors often contain heterogeneous subpopulations of ER tumor cells. We previously identified a population of cyto...
作者:... Jeanelle Sheeder , Carol A. Sartorius , Monique A. Spillman
来源:[J].Gynecologic Oncology(IF 3.929), 2016, Vol.140 (3), pp.518-526Elsevier
摘要:Abstract(#br)Objectives(#br)Endometrial cancer is a hormonally responsive malignancy. Response to progestins is associated with estrogen receptor (ER) and progesterone receptor (PR) status. CD133 is a marker of endometrial cancer stem cells. We postulated that CD133 + cells ...
作者:Jessica Finlay-Schultz , Carol A. Sartorius
来源:[J].Journal of Mammary Gland Biology and Neoplasia(IF 7.524), 2015, Vol.20 (1-2), pp.39-50Springer
摘要:Abstract(#br)The ovarian hormones progesterone and estrogen play important roles in breast cancer etiology, proliferation, and treatment. Androgens may also contribute to breast cancer risk and progression. In recent years, significant advances have been made in defining the role...
作者:Carol A. Sartorius , E. Dale Abel ...
来源:[J].Breast Cancer Research(IF 5.872), 2016, Vol.18 (1)Springer
摘要:Abstract(#br) Background(#br)Altered tumor cell metabolism is an emerging hallmark of cancer; however, the precise role for glucose in tumor initiation is not known. GLUT1 ( SLC2A1 ) is expressed in breast cancer cells and is likely responsible for avid glucose uptake observed in...
作者:Sunshine Daddario Axlund , Carol A. Sartorius
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2012, Vol.357 (1-2), pp.71-79Elsevier
摘要:Abstract(#br)Progesterone plays an important, if not controversial, role in mammary epithelial cell proliferation and differentiation. Evidence supports that progesterone promotes rodent mammary carcinogenesis under some conditions, progesterone receptors (PR) are necessary for m...

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