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作者:Marianne D. van de Wetering , Bart J. Biemond ...
来源:[J].BMC Pediatrics(IF 1.982), 2017, Vol.17 (1)
摘要:Venous thromboembolism (VTE) is a common and severe complication during treatment of acute lymphoblastic leukemia (ALL). An important cause is the intensive use of asparaginase. Prospective cohort studies in which prophylactic low-molecular-weight heparin (LMWH) was used to preve...
作者:... K. Fijnvandraat , Marianne D. van de Wetering , C. Heleen van Ommen
来源:[J].Blood Reviews(IF 6), 2018
摘要:Abstract(#br)The incidence of venous thromboembolism (VTE) in children is rising. Hence, there is an increasing off-label use of low-molecular-weight heparin (LMWH). There is little data about therapeutic and prophylactic LWMH dosages, and their safety and efficacy. This sys...
作者:C. Heleen van Ommen , Theo Stijnen ...
来源:[J].European Journal of Cancer(IF 5.061), 2015, Vol.51 (14), pp.2031-2038
摘要:Abstract(#br)Background(#br)The prevention of central venous catheter (CVC) associated bloodstream infections (CABSIs) in paediatric oncology patients is essential. Ethanol locks can eliminate pathogens colonising CVCs and microbial resistance is rare. Aim of this study was ...
作者:C. Heleen Van Ommen , Marjolein Peters
来源:[J].Thrombosis Research(IF 3.133), 2005, Vol.118 (1), pp.13-25
摘要:Abstract(#br)Pulmonary embolism is an uncommon, but potentially fatal disease in children. Most children with pulmonary embolism have underlying clinical conditions, of which the presence of a central venous catheter is the most frequent. The clinical presentation is often subtle...
作者:C. Heleen van Ommen , Merit M. Tabbers
来源:[J].Thrombosis Research(IF 3.133), 2010, Vol.126 (6), pp.465-470
摘要:Abstract(#br)Survival of children with chronic intestinal failure has increased as result of administration of home parenteral nutrition. Crucial for the successful management of home parenteral nutrition is the availability of an adequate central venous access. Venous access can...
作者:C. Heleen van Ommen , Marjolein Peters
来源:[J].Progress in Pediatric Cardiology, 2005, Vol.21 (1), pp.23-29
摘要:Abstract(#br)In childhood, the incidence of venous thrombosis is increasing, resulting in a growing number of children with complications of this disease, such as the post-thrombotic syndrome. Diagnosis of the post-thrombotic syndrome is based on the presence of typical symptoms ...
作者:... Anne M. J. B. Smets , Aukje Betlem , C. Heleen van Ommen
来源:[J].Journal of Pediatric Hematology/Oncology(IF 0.973), 2015, Vol.37 (6), pp.462-467
摘要:Prescription of thromboprophylaxis is not a common practice in pediatric intensive care units. Most thrombi are catheter-related and asymptomatic, without causing acute complications. However, chronic complications of these (a)symptomatic catheter-related thrombi, that is, postth...
作者:C. Heleen van Ommen , Leslie Raffini ...
来源:[J].Circulation(IF 15.202), 2010, Vol.121 (16), pp.1838-1847
摘要:BACKGROUND—: The aim of this study was to estimate the impact of thrombophilia on risk of first childhood stroke through a meta-analysis of published observational studies. METHODS AND RESULTS—: A systematic search of electronic databases (Medline via PubMed, EMBASE, OVID, W...
作者:C. Heleen van Ommen , Saskia Middeldorp
来源:[J].Semin Thromb Hemost(IF 4.216), 2011, Vol.37 (7), pp.794-801
摘要:Inherited thrombophilia is defined as a genetically determined tendency to develop venous thromboembolism. In children, inherited thrombophilia contributes to the development of pediatric thromboembolic disease. As a consequence, pediatric hematologists are increasingly requested...

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