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作者:Vadim Aksenov , C. David Rollo
来源:[J].Journal of Insect Behavior(IF 0.901), 2017, Vol.30 (3), pp.259-272
摘要:We document that the cricket, Acheta domesticus, avoids “necromone” chemical cues of death associated with treated surfaces and shelters (i.e., ethanol extracts of cricket bodies, oleic acid or linoleic acid). Initially we tested male responses to male body extract, oleic ac...
作者:... Connor J. Nelson , Douglas R. Boreham , C. David Rollo
来源:[J].Dose-Response(IF 1.5), 2018, Vol.16
摘要:Exposure to low-dose ionizing radiation can have positive impacts on biological performance—a concept known as hormesis. Although radiation hormesis is well-documented, the predominant focus has been medical. In comparison, little research has examined potential effects of e...
作者:... Vadim Aksenov , C. David Rollo , Jiankang Liu
来源:[J].Mechanisms of Ageing and Development(IF 3.264), 2012, Vol.133 (8), pp.523-529
摘要:Abstract(#br)We examined whether transgenic growth hormone mice (Tg) that exhibit accelerated cognitive aging and exceptional free radical damage also express elevated nitrative stress. We characterized age-related patterns of 3-nitrotyrosine (3-NT) in brain homogenate and m...
作者:C. David Rollo
来源:[J].Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis(IF 3.902), 2005, Vol.597 (1), pp.18-31
摘要:Abstract(#br)Several recently revealed features of eukaryotic genomes were not predicted by earlier evolutionary paradigms, including the relatively small number of genes, the very large amounts of non-functional code and its quarantine in heterochromatin, the remarkable conserva...
作者:... Asad Lone , Vadim Aksenov , C. David Rollo
来源:[J].AGE(IF 4.084), 2015, Vol.37 (2)
摘要:Abstract(#br)We examined the impacts of aspirin and metformin on the life history of the cricket Acheta domesticus (growth rate, maturation time, mature body size, survivorship, and maximal longevity). Both drugs significantly increased survivorship and maximal life span. Ma...
作者:C. David Rollo
来源:[J].Neurochemical Research(IF 2.125), 2009, Vol.34 (4), pp.601-629
摘要:Abstract(#br)Aging encompasses life itself so understanding requires frameworks that forge unity amidst complexity. The free radical theory of aging is one example. The original focus on damage was augmented recently by appreciation that reactive oxygen and nitrogen species ...
作者:... Parul Khanna , Sarthak Matravadia , C. David Rollo
来源:[J].AGE(IF 4.084), 2013, Vol.35 (1), pp.23-33
摘要:Abstract(#br)We developed a complex dietary supplement designed to offset five key mechanisms of aging and tested its effectiveness in ameliorating age-related cognitive decline using a visually cued Morris water maze test. All younger mice (<1 year old) learned the task wel...
作者:... Wida Naikkhwah , Vadim Aksenov , C. David Rollo
来源:[J].AGE(IF 4.084), 2011, Vol.33 (4), pp.509-522
摘要:Abstract(#br)Studying aging is constrained using vertebrates by their longevity, size, ethical restrictions, and expense. The key insect model, Drosophila melanogaster , is holometabolous. Larvae feed on yeast in moist media and adults sponge food. Most aging studies are res...
作者:Jonathan Tran , Vadim Aksenov , C. David Rollo
来源:[J].Entomologia Experimentalis et Applicata(IF 1.669), 2018, Vol.166 (1), pp.63-73
摘要:Abstract(#br)Nutrition is a key component of life‐history theory with profound impacts on fitness traits. We examined lifetime impacts of a multi‐ingredient athletic supplement ( MAS ) on physical performance, anatomical morphology, survivorship, and general life‐histor...

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