全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Cécile Croix , Anne-Sophie Lamort ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2017Elsevier
摘要:Abstract(#br)Cathepsin C (CatC) is a tetrameric cysteine dipeptidyl aminopeptidase that plays a key role in activation of pro-inflammatory serine protease zymogens by removal of a N-terminal pro-dipeptide sequence. Loss of function mutations in the CatC gene is associated wi...
作者:Cécile Croix , Lucie Jaquillard ...
来源:[J].Biochemical Pharmacology(IF 4.576), 2012, Vol.83 (6), pp.788-796Elsevier
摘要:Abstract(#br)The biological functions of human neutrophil proteinase 3 (PR3) remain unclear because of its close structural resemblance to neutrophil elastase and its apparent functional redundancy with the latter. Thus, all natural inhibitors of PR3 preferentially target ne...
作者:Cécile Croix , Hélène Laborie ...
来源:[J].Journal of Pharmaceutical and Biomedical Analysis(IF 2.947), 2010, Vol.54 (2), pp.411-416Elsevier
摘要:Abstract(#br)A new method based on high-performance liquid chromatography coupled to ultraviolet and evaporative light scattering detection (HPLC-UV-ELSD) was developed for the determination of l -glutamic acid, a potential degradation product of pemetrexed, and for the quan...
作者:Cécile Croix , David Alagille ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2010, Vol.21 (3), pp.1019-1022Elsevier
摘要:Abstract(#br)Several thalidomide analogues were synthesized and compared to thalidomide and its more active analogue, lenalidomide, for their ability to inhibit the production of the pro-inflammatory cytokine tumour necrosis factor (TNF)-α and interleukin (IL)-6 by LPS-activ...
作者:Agathe Souffrin , Cécile Croix , Marie‐Claude Viaud‐Massuard
来源:[J].European Journal of Organic Chemistry(IF 3.344), 2012, Vol.2012 (13), pp.2499-2502Wiley
摘要:Abstract(#br)Maleimides are involved for the first time in Sonogashira cross‐coupling reactions. Sonogashira conditions have been developed to allow subsequent coupling of various terminal alkynes at room temperature in moderate to excellent yields. These results open the wa...
作者:Cécile Croix , Joan Basset ...
来源:[J].Synlett(IF 2.655), 2010, Vol.2010 (10), pp.1481-1484Thieme
摘要:A mild method for the desulfonylation of N-indolesand N-azaindoles is described. Deprotectionis carried out under basic conditions, using sodium TERT-butoxide in dioxane. Several functionalizedindoles and 7-azaindoles were efficiently deprotected by this method,which is mild enou...

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