全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Meggan Mackay , Cynthia Aranow , Betty Diamond
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.4 (6)DOAJ
摘要:DNA-reactive B cells play a central role in systemic lupus erythematosus (SLE); DNA antibodies precede clinical disease and in established disease correlate with renal inflammation and contribute to dendritic cell activation and high levels of type 1 interferon. A number of ...
作者:... Gary S Gilkeson , Betty Diamond , John A Hardin
来源:[J].PLoS ONE(IF 3.73), 2010, Vol.5 (2)DOAJ
摘要:Excessive activity of dendritic cells (DCs) is postulated as a central disease mechanism in Systemic Lupus Erythematosus (SLE). Vitamin D is known to reduce responsiveness of healthy donor DCs to the stimulatory effects of Type I IFN. As vitamin D deficiency is reportedly common ...
作者:Betty Diamond , Daniel Rotrosen ...
来源:[J].Clinical Immunology(IF 3.771), 2014, Vol.150 (2), pp.A1-A2Elsevier
作者:... Czeslawa Kowal , Bruce T. Volpe , Betty Diamond
来源:[J].Trends in Immunology(IF 9.486), 2015, Vol.36 (11), pp.709-724Elsevier
摘要:The brain is normally sequestered from antibody exposure by the blood brain barrier. However, antibodies can access the brain during fetal development before the barrier achieves full integrity, and in disease states when barrier integrity is compromised. Recent studies suggest t...
作者:Sun Jung Kim , Betty Diamond
来源:[J].Seminars in Cell and Developmental Biology(IF 6.202), 2015, Vol.41, pp.49-58Elsevier
摘要:Abstract(#br)A key function of dendritic cells (DCs) is to induce either immune tolerance or immune activation. Many new DC subsets are being recognized, and it is now clear that each DC subset has a specialized function. For example, different DC subsets may express different ce...
作者:... Justine Calise , Susan Malkiel , Betty Diamond
来源:[J].Current Opinion in Immunology(IF 8.771), 2016, Vol.43, pp.1-7Elsevier
摘要:IgG anti-DNA antibodies are both diagnostic and pathogenic for systemic lupus erythematosus (SLE). They contribute to tissue inflammation through direct tissue binding and to systemic inflammation through activation of Toll-like receptors by nucleic acid-containing immune complex...

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