全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Eric Kipnis , Bertrand Toussaint , Audrey Le Gouellec
来源:[J].BMC Microbiology(IF 3.104), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br) Pseudomonas aeruginosa (Pa) is a Gram-negative bacteria frequently involved in healthcare-associated pneumonia with poor clinical outcome. To face the announced post-antibiotic era due to increasing resistance and lack of new antibiotics, new tr...
作者:Bertrand Toussaint , Alicia Fournier ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (9)DOAJ
摘要:Crohn's disease (CD) and irritable bowel syndrome (IBS) involve brain-gut dysfunctions where vagus nerve is an important component. The aim of this work was to study the association between vagal tone and markers of stress and inflammation in patients with CD or IBS compared to h...
作者:Bertrand Toussaint , Jean Luc Lenormand
来源:[J].International Journal of Pharmaceutics(IF 3.458), 2017, Vol.529 (1-2), pp.65-74Elsevier
摘要:Abstract(#br)Transcription factors (TFs) are key actors of the control of gene expression and consequently of every major process within cells, ranging from cell fate determination, cell cycle control and response to environment. Their ectopic expression has proven high potential...
作者:Bertrand Toussaint , Thierry Lequerré ...
来源:[J].Joint Bone Spine(IF 2.748), 2018Elsevier
摘要:Abstract(#br)Objectives(#br)Tumour necrosis factor-alpha inhibitors (TNFi) are effective treatments for Rheumatoid Arthritis (RA). Responses to treatment are barely predictable. As these treatments are costly and may induce a number of side effects, we aimed at identifying a...
作者:... Boubou Camara , Bertrand Toussaint , Audrey Le Gouëllec
来源:[J].Vaccine(IF 3.492), 2018, Vol.36 (14), pp.1893-1900Elsevier
摘要:Abstract(#br)Pseudomonas aeruginosa (Pa) is a significant cause of morbidity and mortality, especially in cystic fibrosis patients. Its eradication is difficult due to a wide phenotypic adaptability and an increase of its resistance to antibiotics. After the failure of several re...
作者:Bertrand Toussaint , Philippe Gaudin
来源:[J].Joint Bone Spine(IF 2.748), 2019Elsevier
摘要:ABSTRACT(#br)Calprotectin is a calcium binding protein produced by neutrophils and monocytes locally at the site of inflammation in order to trigger the innate immunity receptors. This unique characteristic makes it a good proxy for evaluation of local inflammation in chronic inf...
作者:... Sébastien Bailly , Bertrand Toussaint , Pascal Mossuz
来源:[J].Experimental Hematology(IF 2.907), 2014, Vol.42 (5), pp.360-368Elsevier
摘要:Studies have shown that the clinical impact of Janus kinase 2 (JAK2) inhibitors in primary myelofibrosis patients is due to the regulation of cytokine levels, suggesting that cytokine profiles might play a critical role in myeloproliferative neoplasms (MPNs) physiopathology....
作者:... Benoit Guery , Bertrand Toussaint , Marie José Stasia
来源:[J].Free Radical Biology and Medicine(IF 5.271), 2014, Vol.73, pp.400-410Elsevier
摘要:Abstract(#br)Pseudomonas aeruginosa is responsible for persistent infections in cystic fibrosis patients, suggesting an ability to circumvent innate immune defenses. This bacterium uses the kynurenine pathway to catabolize tryptophan. Interestingly, many host cells also prod...

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