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作者:... Krystiana A. Krzyśko , Andrzej Kochański , Barbara Zabłocka
来源:[J].Scientific Reports(IF 2.927), 2018, Vol.8 (1), pp.1-11
摘要:Abstract Charcot-Marie-Tooth disease type 2A (CMT2A is an autosomal dominant neuropathy caused by mutations in the mitofusin 2 gene (MFN2. More than 100 MFN2 gene mutations have been reported so far, with majority located within the GTPase domain encoding region. These domain-spe...
作者:... Andrzej Kochański , Krystiana A Krzyśko , Barbara Zabłocka
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (1)
摘要:Charcot-Marie-Tooth disease type 2A (CMT2A) is an autosomal dominant axonal peripheral neuropathy caused by mutations in the mitofusin 2 gene (MFN2). Mitofusin 2 is a GTPase protein present in the outer mitochondrial membrane and responsible for regulation of mitochondrial networ...
作者:Barbara Zabłocka , Katarzyna Maternicka ...
来源:[J].Brain Research(IF 2.879), 1998, Vol.779 (1), pp.254-258
摘要:Abstract(#br)Cerebral ischemia is known to modify the expression of genetic information in the brain. To complement this knowledge, in the present study we have estimated the expression of calcium- and phospholipid-dependent (classical) protein kinase C (c PKC) isoform mRNAs...
作者:Małgorzata Beręsewicz , Joanna E. Kowalczyk , Barbara Zabłocka
来源:[J].Neurochemistry International(IF 2.659), 2005, Vol.48 (6), pp.568-571
摘要:Abstract(#br)Previously we have shown that the biphasic efflux of mitochondrial protein cytochrome c to cytoplasm is one of the important events of the delayed postichemic neuronal death. We concluded that early and transient appearance of cytochrome c in cytoplasm of cells recov...
作者:... Małgorzata Beręsewicz , Barbara Zabłocka , Krystyna Domańska-Janik
来源:[J].Neurochemistry International(IF 2.659), 2009, Vol.55 (1), pp.164-173
摘要:Abstract(#br)The aim of the present investigation was to analyze the molecular mechanism(s) of diazepam neuroprotection in two models of selective neuronal death in CA1 sector of hippocampus: in vivo following transient gerbil brain ischemia and in vitro in rat hippocampal b...
作者:Dariusz C. Górecki , Małgorzata Beręsewicz , Barbara Zabłocka
来源:[J].Neurochemistry International(IF 2.659), 2007, Vol.51 (8), pp.451-458
摘要:Abstract(#br)Insulin-like growth factor I (IGF-1) is a peptide synthesized in response to growth hormone stimulation. While most of the circulating IGF-1 comes from the liver, it can also be produced in other tissues and both its expression and processing undergo tissue-specific ...
作者:... Anna Dybel , Barbara Zabłocka , Jan Albrecht
来源:[J].Neurochemistry International(IF 2.659), 2003, Vol.43 (4), pp.501-507
摘要:Abstract(#br)Previous studies from this laboratory have shown that glutamine (Gln) uptake in a rat astrocytoma-derived C6 cell line shows characteristics similar with the uptake of a model ASC system substrate, threonine, whose pH-dependence and partial tolerance of Li + sub...
作者:... Janusz Dębski , Michał Dadlez , Barbara Zabłocka
来源:[J].Mitochondrion(IF 4.025), 2012, Vol.12 (1), pp.138-143
摘要:Abstract(#br)PKC is implicated in the regulation of mitochondrial metabolism. We examined the association of PKCβ with mitochondria and followed postischemic changes in its amount in mitochondria isolated from ischemia-vulnerable (CA1) and ischemia-resistant (CA2–4,DG) hippo...
作者:... Piotr Bednarczyk , Barbara Zabłocka , Krzysztof Dołowy
来源:[J].FEBS Letters(IF 3.582), 2010, Vol.584 (10), pp.2063-2069
摘要:Abstract(#br)Mitochondrial potassium channels play an important role in cytoprotection. Potassium channels in the inner mitochondrial membrane are modulated by inhibitors and activators (potassium channel openers) previously described for plasma membrane potassium channels. The m...

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