全部文献期刊会议图书|学者科研项目
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作者:Balázs Győrffy , Peter Schirmacher
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)
摘要:Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients emphasizing the need for powerful biomarkers that ...
作者:... Gyula Richárd Nagy , Ildikó Vereczkey , Balázs Győrffy
来源:[J].Gynecologic Oncology(IF 3.929), 2020, Vol.156 (3), pp.654-661
摘要:Abstract(#br)Objective(#br)The first-line chemotherapy for ovarian cancer is based on a combination of platinum and taxane. To date, no reliable predictive biomarker has been recognized that is capable of identifying patients with pre-existing resistance to these agents. Here, we...
作者:Balázs Győrffy , Nancy Adriana Espinoza-Sánchez
来源:[J].Scientific Reports(IF 2.927), 2020, Vol.10 (1), pp.227-227
摘要:Abstract(#br)In several carcinomas, the SET Domain Containing 3, Actin Histidine Methyltransferase (SETD3) is associated with oncogenesis. However, there is little knowledge about the role of SETD3 in the progression and prognosis of breast cancer. In this study, we first an...
作者:Balázs Győrffy , Roberta Tarallo ...
来源:[J].Cancer Letters(IF 4.258), 2018, Vol.437
摘要:Abstract(#br)Cancer-associated Fibroblasts (CAFs), the principal components of tumor microenvironment, play multiple role in breast cancer progression. We have previously shown an oncosuppressive role of the nuclear Farnesoid X Receptor (FXR) in mammary epithelial cancer cells, h...
作者:Balázs Győrffy , Lilla Madaras ...
来源:[J].Human Pathology(IF 2.843), 2017, Vol.65
摘要:Summary(#br)Although several antibodies are available for immunohistochemical detection of Ki-67, even the most commonly used MIB-1 has not been validated yet. Our aim was to compare 5 commercially available antibodies for detection of Ki-67 in terms of agreement and their a...
作者:Balázs Győrffy , Luciane R. Cavalli
来源:[J].Molecular and Cellular Endocrinology(IF 4.039), 2018, Vol.471, pp.105-117
摘要:Abstract(#br)Invasive lobular breast cancer (ILC) is an understudied malignancy with distinct clinical, pathological, and molecular features that distinguish it from the more common invasive ductal carcinoma (IDC). Mounting evidence suggests that estrogen receptor-alpha positive ...
作者:Balázs Győrffy , Pawel Surowiak ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)
摘要:In the last decade, optimized treatment for non-small cell lung cancer had lead to improved prognosis, but the overall survival is still very short. To further understand the molecular basis of the disease we have to identify biomarkers related to survival. Here we present the de...
作者:... Atanasio Pandiella , Balázs Győrffy , Alberto Ocaña
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (5)
摘要:Most patients with early stage triple negative breast cancer (TNBC) receive adjuvant chemotherapy. Activation of the immune system is associated with tumor response and may help identify TNBC with favorable outcome.Gene expression data were obtained from the GEO Dataset GDS2250/G...
作者:... Attila Szendrői , Reinhold Schäfer , Balázs Győrffy
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (3)
摘要:Because of the low overall response rates of 10-47% to targeted cancer therapeutics, there is an increasing need for predictive biomarkers. We aimed to identify genes predicting response to five already approved tyrosine kinase inhibitors. We tested 45 cancer cell lines for sensi...
作者:Gyöngyi Munkácsy , Péter Herman , Balázs Győrffy
来源:[J].Scientific Reports(IF 2.927), 2019, Vol.9 (1), pp.1-6
摘要:Abstract Although numerous studies containing induced gene expression have already been published, independent authentication of their results has not yet been performed. Here, we utilized available transcriptomic data to validate the achieved efficiency in overexpression studies...

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