全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Balázs Győrffy , Peter Schirmacher
来源:[J].BMC Medical Genomics(IF 3.466), 2017, Vol.10 (1)Springer
摘要:Inhibition of the PD-L1/PD-1 immune checkpoint axis represents one of the most promising approaches of immunotherapy for various cancer types. However, immune checkpoint inhibition is successful only in subpopulations of patients emphasizing the need for powerful biomarkers that ...
作者:Balázs Győrffy , Pawel Surowiak ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (12)DOAJ
摘要:In the last decade, optimized treatment for non-small cell lung cancer had lead to improved prognosis, but the overall survival is still very short. To further understand the molecular basis of the disease we have to identify biomarkers related to survival. Here we present the de...
作者:Balázs Győrffy , László Harsányi
来源:[J].Diagnostic Pathology(IF 1.85), 2016, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)Phosphatase and tensin homolog deleted in chromosome 10 (PTEN) loss of function is frequently detected in advanced colorectal cancer. Its detection is thought to have prognostic significance and it is being considered to predict responsiveness to anti...
作者:... Roberto Vera , Balázs Győrffy , Sándor Pongor
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.10 (6)DOAJ
摘要:Drug combinations are highly efficient in systemic treatment of complex multigene diseases such as cancer, diabetes, arthritis and hypertension. Most currently used combinations were found in empirical ways, which limits the speed of discovery for new and more effective combinati...
作者:... Atanasio Pandiella , Balázs Győrffy , Alberto Ocaña
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.12 (5)DOAJ
摘要:Most patients with early stage triple negative breast cancer (TNBC) receive adjuvant chemotherapy. Activation of the immune system is associated with tumor response and may help identify TNBC with favorable outcome.Gene expression data were obtained from the GEO Dataset GDS2250/G...
作者:... Attila Szendrői , Reinhold Schäfer , Balázs Győrffy
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.8 (3)DOAJ
摘要:Because of the low overall response rates of 10-47% to targeted cancer therapeutics, there is an increasing need for predictive biomarkers. We aimed to identify genes predicting response to five already approved tyrosine kinase inhibitors. We tested 45 cancer cell lines for sensi...
作者:Balázs Győrffy , Richard P Lifton ...
来源:[J].PLoS Medicine(IF 16.269), 2016, Vol.13 (12)DOAJ
摘要:Triple negative breast cancer (TNBC) is a highly heterogeneous and aggressive disease, and although no effective targeted therapies are available to date, about one-third of patients with TNBC achieve pathologic complete response (pCR) from standard-of-care anthracycline/taxane (...
作者:... András Szabó , Libero Santarpia , Balázs Győrffy
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2016, Vol.160 (3), pp.439-446Springer
摘要:Abstract(#br) Purpose(#br)The proper validation of prognostic biomarkers is an important clinical issue in breast cancer research. MicroRNAs (miRNAs) have emerged as a new class of promising breast cancer biomarkers. In the present work, we developed an integrated online bio...
作者:Balázs Győrffy , Zsombor Benke ...
来源:[J].Breast Cancer Research and Treatment(IF 4.469), 2012, Vol.132 (3), pp.1025-1034Springer
摘要:Abstract(#br)In the last decades, several gene expression-based predictors of clinical behavior were developed for breast cancer. A common feature of these is the use of multiple genes to predict hormone receptor status and the probability of tumor recurrence, survival or re...
作者:Balázs Győrffy , Andrea Magda Nagy ...
来源:[J].Scientometrics(IF 2.133), 2018, Vol.117 (1), pp.409-426Springer
摘要:Abstract(#br)The Momentum program launched in 2009 provides funding of up to 1 million Euro to establish new, independent research groups at Hungarian academic institutions. Here, our aim was to determine factors associated with the scientific output of these research groups...

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