全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Holger Moch , Aurelia Noske , Konstantin J. Dedes
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:BRCA1/2-deficient ovarian carcinomas are recognized as target for Poly (ADP-ribose) polymerase (PARP) inhibitors. BRCA1 and BRCA2 proteins are involved in homologous recombination repair of double-strand DNA breaks. The relevance of other homologous recombination repair proteins,...
作者:Aurelia Noske , Eleftherios P. Samartzis ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Endometrioid adenocarcinoma of the uterus and ovarian endometrioid carcinoma share many morphological and molecular features. Differentiation between simultaneous primary carcinomas and ovarian metastases of an endometrial cancer may be very challenging but is essential for progn...
作者:Aurelia Noske , Michael Schwabe ...
来源:[J].BMC Cancer(IF 3.333), 2011, Vol.11 (1)Springer
摘要:Abstract(#br) Background(#br)In ovarian cancer, the reported rate of EGFR expression varies between 4-70% depending on assessment method and data on patient outcome are conflicting. Methods: In this study we investigated EGFR expression and its prognostic value in a cohort of 121...
作者:Aurelia Noske , Alexander Meisel ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (1)DOAJ
摘要:INTRODUCTION: The G protein-coupled estrogen receptor (GPER) is a novel estrogen receptor that mediates proliferative effects induced by estrogen but also by tamoxifen. The aim of our study was to analyze the frequency of GPER in a large collective of primary invasive breast carc...
作者:Aurelia Noske , Adriana von Teichman ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.9 (6)DOAJ
摘要:To evaluate the frequency of MRE11/RAD50/NBS1 (MRN)-complex loss of protein expression in endometrial cancers (EC) and to determine whether loss of MRE11 renders the cancer cells sensitive to Poly(ADP-ribose) polymerase (PARP)-inhibitory treatment.MRN expression was examined in 5...
作者:Aurelia Noske , Ellen Obermann ...
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (5)DOAJ
摘要:UNLABELLED: Adjuvant chemotherapy decisions in breast cancer are increasingly based on the pathologist's assessment of tumor proliferation. The Swiss Working Group of Gyneco- and Breast Pathologists has surveyed inter- and intraobserver consistency of Ki-67-based proliferative fr...

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