全部文献期刊会议图书|学者科研项目
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作者:Athina Giagini , Alkiviadis Kostakis
来源:[J].Digestive Diseases and Sciences(IF 2.26), 2008, Vol.53 (5), pp.1289-1296Springer
摘要:Abstract(#br)Thymidylate synthase (TS) is an enzyme responsible for DNA synthesis. Its competitive inhibition constitutes the major mechanism of the antitumor effect of 5-fluorouracil (5-FU) therapy, which significantly improves the survival rate of colon cancer patients. Th...
作者:Athina Giagini , Gerasimos Tsourouflis ...
来源:[J].Digestive Diseases and Sciences(IF 2.26), 2011, Vol.56 (3), pp.777-785Springer
摘要:Abstract(#br) Background(#br)Minichromosome maintenance (MCM) proteins are essential components of DNA replication, being related to cell proliferation, and serve as useful biomarkers for cancer screening, surveillance and prognosis. The aim of the present study was to evaluate t...
作者:Athina Giagini , Ioannis Adamakis ...
来源:[J].Medical Oncology(IF 2.147), 2018, Vol.35 (7), pp.1-6Springer
摘要:Abstract(#br)The goal of the study is to examine the possible use of HA (hyaluronic acid) and HAase (hyaluronidase) as novel urine biomarkers for the early diagnosis for prostate cancer (Pca). After a prostatic massage, the urine of 118 high-risk patients for Pca was collected, a...
作者:Athina Giagini , Efstratios Patsouris
来源:[J].Pathology & Oncology Research(IF 1.555), 2016, Vol.22 (1), pp.189-196Springer
摘要:Abstract(#br)Hu-antigen R (HuR) is considered to play a crucial role in tumor formation and growth by binding to mRNAs encoding proteins such as Cyclooxygenase-2 (COX-2) and inducing their expression via mRNA stabilization and/or altered translation. The present study aimed ...
作者:Costas Giaginis , Athina Giagini , Stamatios Theocharis
来源:[J].Pharmacological Research(IF 4.346), 2009, Vol.60 (3), pp.160-169Elsevier
摘要:Abstract(#br)Peroxisome proliferator-activated receptor-γ (PPAR-γ) has already been considered as an attractive molecular target for the treatment of human metabolic disorders. Pleiotropic functions beyond this limit, such as anti-inflammatory and anti-proliferative effects ...
作者:Athina Giagini , Zeta Papadopoulou-Daifoti ...
来源:[J].Journal of Alzheimer's Disease(IF 4.174), 2018, Vol.64 (3), pp.787-800IOS Press
摘要:Background: Natural products are a significantly underutilized source of potential treatments against human disease. Alzheimer’s disease (AD) is a prime example of conditions that could be amenable to such treatments as suggested by recent findings. Objective: Aiming to iden...

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