全部文献期刊会议图书|学者科研项目
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作者:... William G. Ondo , Arthur S. Walters , John W. Winkelman
来源:[J].Mayo Clinic Proceedings(IF 5.79), 2018, Vol.93 (1), pp.59-67
摘要:Abstract(#br)Restless legs syndrome (RLS) is a distinct disorder, differing from chronic pain in many ways. Refractory RLS is characterized by unresponsiveness to dopamine agonists or alpha-2-delta ligands due to inadequate efficacy, augmentation, or adverse effects. This may res...
作者:... Alexander Oksche , Arthur S. Walters , Yuqing Li
来源:[J].Behavioural Brain Research(IF 3.327), 2019, Vol.374
摘要:Abstract(#br)Previous studies have uncovered a potential role of the opioid system in iron hemostasis and dopamine metabolism. Abnormalities in both of these systems have been noted in human RLS. Autopsy studies of human RLS have shown an endogenous opioid deficiency in the thala...
作者:Arthur S. Walters , Kimberly Doggett ...
来源:[J].Sleep Medicine(IF 3.487), 2017, Vol.32, pp.48-55
摘要:Abstract(#br)Objective(#br)To investigate the pharmacokinetics (PK) of rotigotine transdermal system in adolescents with moderate-to-severe idiopathic restless legs syndrome (RLS).(#br)Methods(#br)This multicenter, open-label, dose-escalation study enrolled patients ≥13 to <...
作者:Arthur S. Walters , Luigi Ferini Strambi ...
来源:[J].Sleep Medicine(IF 3.487), 2018
摘要:Abstract(#br)Introduction(#br)The International Restless Legs Study Group (IRLSSG) has developed the IRLS (International Restless Legs Syndrome Severity Scale) and validated it as a clinician/researcher administered scale to be used when both patient and examiner are present...
作者:... Tiffany J. Braley , Arthur S. Walters , Robert W. Motl
来源:[J].Journal of the Neurological Sciences(IF 2.243), 2019, Vol.407
摘要:Abstract(#br)The present study examined the relationships among parameters (i.e., volume and pattern) of physical activity and sedentary behavior with the presence and severity of restless legs syndrome(RLS) in adults with multiple sclerosis(MS). Participants with MS ( N = 253) w...
作者:... Birgit Högl , Elmar Dunkl , Arthur S. Walters
来源:[J].Sleep Medicine(IF 3.487), 2016, Vol.20, pp.116-122
摘要:Abstract(#br)Background(#br)The International Restless Legs Scale (IRLS) is the most widely used of the scales rating the severity of restless legs syndrome/Willis–Ekbom disease (RLS/WED). It has been well validated and is the primary end point for most of the therapeutic an...
作者:... Birgit Högl , Elmar Dunkl , Arthur S. Walters
来源:[J].Sleep Medicine(IF 3.487), 2016, Vol.24, pp.10-17
摘要:Abstract(#br)Background(#br)Due to the symptoms and the sleep disturbances it causes, Restless Legs Syndrome (RLS) has a negative impact on quality of life. Measurement of such impact can be performed by means of questionnaires, such as the Kohnen Restless Legs Syndrome–Qual...
作者:Arthur S. Walters , David Gabelia , Birgit Frauscher
来源:[J].Sleep Medicine(IF 3.487), 2013, Vol.14 (12), pp.1247-1252
摘要:Abstract(#br)There has been no previous side-by-side comparison of the diagnostic criteria for restless legs syndrome (RLS) (Willis–Ekbom disease) and growing pains. In our review, we explore this comparison emphasizing overlaps and disconnects, summarize recent literature e...

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