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作者:Ghedeir M. Alshammari , Aristatile Balakrishnan , Thirunavukkarasu Chinnasamy
来源:[J].Inflammation Research(IF 1.964), 2017, Vol.66 (9), pp.753-763Springer
摘要:Liver inflammation stimulates various inflammatory cytokines and initiates injury through oxidative stress. The aim of this study was to curtaile the liver injury through natural principles such as 2-hydroxy-4-methoxy benzoic acid (HMBA).
作者:Ghedeir M. Alshammari , Aristatile Balakrishnan , Thirunavukkarasu Chinnasamy
来源:[J].Molecular Biology Reports(IF 2.506), 2017, Vol.44 (6), pp.463-474Springer
摘要:Nimbolide is a bioactive compound found in Azadirachta indica . This work was devised to investigate the potential effects of nimbolide on intracellular lipid deposition and its associated redox modulation in primary hepatocytes (Heps). Lipid accumulation was induced in Heps...
作者:Aristatile Balakrishnan , Ghedeir M. Alshammari
来源:[J].Journal of Pharmaceutical and Biomedical Analysis(IF 2.947), 2018, Vol.154, pp.294-301Elsevier
摘要:Abstract(#br)Drug repurposing has been an emerging therapeutic strategy, which involves exploration of a new therapeutic approach for the use of an existing drug. Glibenclamide (Gli) is an anti-diabetic sulfonylurea drug extensively used for the treatment of type-2 diabetes,...
作者:Ghedeir M. Alshammari , Aristatile Balakrishnan , Thirunavukkarasu Chinnasamy
来源:[J].Journal of Food Biochemistry(IF 0.756), 2018, Vol.42 (5), pp.n/a-n/aWiley
摘要:Abstract(#br)The current research was focused at investigating the different doses of germinated mung bean (GMB) ( Vigna Radiata [Fabaceae]) on progression of non‐alcoholic steatohepatitis (NASH) from steatosis. Beneficial effects of GBM against NASH from steatosis‐induced l...
作者:Ghedeir M. Alshammari , Aristatile Balakrishnan , Thirunavukkarasu Chinnasamy
来源:[J].BioFactors(IF 3.088), 2018, Vol.44 (3), pp.289-298Wiley
摘要:Abstract(#br)One of the worldwide metabolic health dilemma is nonalcoholic fatty liver diseases (NAFLD). Researchers are searching effective drug to manage NAFLD patients. One of the best way to manage the metabolic imperfection is through natural principal isolated from dif...
作者:Ghedeir M. Alshammari , Aristatile Balakrishnan
来源:[J].Saudi Journal of Biological Sciences, 2019, Vol.26 (4), pp.744-751Elsevier
摘要:Abstract(#br)Prevention and management of obesity through dietary modification is one of the top way to trim down its consequences. Development of adipose tissue requires the differentiation of less specialized cells, such as human mesenchymal stem cells (hMSCs), into adipocytes....
作者:Aristatile Balakrishnan , Alshammari Ghedeir M
来源:[J].Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2017, Vol.89, pp.215-220PubMed
摘要:Cucurbita ficifolia (C. ficifolia) has been traditionally known for its medicinal properties as an antioxidant, anti-diabetic and anti-inflammatory agent. However, there has been an enduring attention towards the identification of unique method, to isolate the natural components ...
作者:Aristatile Balakrishnan , Dharuman Venkataraman
来源:[J].Chemico-biological interactions, 2017PubMed
摘要:Therapeutic applications of arsenic trioxide (ATO) are limited due to their severe adverse effects. However, nanoparticles of ATO might possess inimitable biologic effects based on their structure and size which differ from their parent molecules. Based on this conception, AsNPs ...
作者:Aristatile Balakrishnan , Al-Numair Khalid S ...
来源:[J].Journal of biochemical and molecular toxicology, 2015, Vol.29 (11), pp.497-507PubMed
摘要:Exposure to ultraviolet B (UVB; 280-320 nm) radiation induces the formation of reactive oxygen species (ROS) in the biological system. In this study, we examined the protective effect of carvacrol on UVB-induced lipid peroxidation and oxidative DNA damage with reference to a...

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