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作者:Luke S. J. Wilson , Antonio Martinez
来源:[J].Journal of Computational Electronics(IF 1.013), 2017, Vol.16 (3), pp.497-502
摘要:We present a first-principles study of the conductance of Guanine and 8-Oxoguanine (8-oxoG) attached to Au(111) electrodes. Cellular levels of 8-oxoG have been found in larger concentrations in cancer patients. The current through the structure was calculated using a DFT–NEG...
作者:Antonio Martinez , Jose A. Lupiañez
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2018, Vol.148, pp.325-336
摘要:Abstract(#br)A set of 18 amide derivatives of oleanolic or maslinic acid has been semi-synthesised. Twelve were diamine conjugates at C-28 of these triterpenic acids and the other six were PEGylated-diamine derivatives. The cytotoxic effects of these 18 triterpenic derivativ...
作者:... Marta del Pino , Antonio Martinez , Jaume Ordi
来源:[J].Digestive and Liver Disease(IF 3.162), 2017
摘要:Abstract(#br)Background(#br)Experience in the use of whole slide imaging (WSI) for primary diagnosis is limited and there are no comprehensive reports evaluating this technology in liver biopsy specimens.(#br)Aims(#br)To determine the accuracy of interpretation of WSI compar...
作者:Antonio Martinez , Alberto Perojil ...
来源:[J].Tetrahedron(IF 2.803), 2015, Vol.71 (5), pp.792-800
摘要:Abstract(#br)The semi-syntheses of taraxerane triterpenoids by diverse bromination processes and other reactions, from oleanolic acid and some closely related derivatives, have been performed. For all the reactions performed, suitable mechanisms to explain the formation of these ...
作者:Antonio Martinez , Alberto Perojil ...
来源:[J].Phytochemistry(IF 3.05), 2015, Vol.117, pp.500-508
摘要:Abstract(#br)The pentacyclic triterpenoids methyl oleanolate, methyl maslinate, methyl 3β-hydroxyolean-9(11),12-dien-28-oate, and methyl 2α,3β-dihydroxy-12β,13β-epoxyolean-28-oate were biotransformed by Rhizomucor miehei CECT 2749. Microbial transformation of methyl ole...
作者:Antonio Martinez , Samuel Martin-Fonseca ...
来源:[J].European Journal of Medicinal Chemistry(IF 3.499), 2016, Vol.118, pp.64-78
摘要:Abstract(#br)Several PEGylated derivatives of oleanolic and maslinic acids have been semi-synthesized, attaching one acid-PEG reagent to the hydroxyl group/s at C-2 or C-2/C-3 of the A rings of these natural triterpenes, and also to their corresponding C-28 benzyl derivative...
作者:Antonio Martinez , Beatriz Bellosillo ...
来源:[J].The American Journal of Pathology(IF 4.522), 2004, Vol.164 (2), pp.501-510
摘要:Survivin is a member of the inhibitor of apoptosis protein family that is expressed in G2/M phase. Survivin is overexpressed and associated with parameters of poor prognosis in different human tumors. The role of survivin in the pathogenesis of mantle cell lymphoma (MCL) was exam...
作者:Antonio Martinez , Francisco Rivas ...
来源:[J].Phytochemistry(IF 3.05), 2013, Vol.94, pp.229-237
摘要:Abstract(#br)Microbial transformation of oleanolic acid by Rhizomucor miehei produced three metabolites. A known compound, a 30-hydroxyl derivative (queretaroic acid), and two 7β,30- and 1β,30-dihydroxylated metabolites, respectively. The action of the same fungus ( R. miehe...
作者:Antonio Martinez , Jose C. Valverde
来源:[J].Applied Mathematics and Computation(IF 1.349), 2008, Vol.210 (1), pp.33-38
摘要:Abstract(#br)For a family of continuous-time dynamical systems, in [F. Balibrea, A. Martinez, J.C. Valverde, Local bifurcations of one-dimensional continuous dynamical systems under higher order conditions, in press] we gave sufficient conditions of higher order in terms of the f...
作者:... Carmelo Serrano , Maria Isabel Benavent , Antonio Martinez
来源:[J].European Journal of Radiology(IF 2.512), 1998, Vol.27 (2), pp.149-152
摘要:Abstract(#br)A 14 year-old boy with X-linked chronic granulomatous disease (CGD) developed a long smooth narrowing at the mid oesophagus with severe dysphagia. Endoscopy revealed a normal mucosa and biopsy showed non-specific acute inflammatory changes. Bacterial cultures of the ...

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