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作者:Anthony Bougas , Ioannis A. Vlachogiannis ...
来源:[J].Amino Acids(IF 3.914), 2017, Vol.49 (5), pp.995-1004Springer
摘要:Chloramphenicol peptides were recently established as useful tools for probing nascent polypeptide chain interaction with the ribosome, either biochemically, or structurally. Here, we present a new 10mer chloramphenicol peptide, which exerts a dual inhibition effect on the riboso...
作者:Anthony Bougas , Maria Stavropoulou ...
来源:[J].Journal of Enzyme Inhibition and Medicinal Chemistry(IF 1.495), 2016, Vol.31 (2), pp.276-282Taylor & Francis
摘要:Abstract(#br)Ketolides belong to the latest generation of macrolides and are not only effective against macrolide susceptible bacterial strains but also against some macrolide resistant strains. Here we present data providing insights into the mechanism of action of K-1602, ...

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