全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Annette N. Ratcliff , Menakshi Bhat ...
来源:[J].Retrovirology(IF 5.657), 2017, Vol.14 (1)Springer
摘要:Like all viruses, HIV-1 relies on host systems to replicate. The human purinome consists of approximately two thousand proteins that bind and use purines such as ATP, NADH, and NADPH. By virtue of their purine binding pockets, purinome proteins are highly druggable, and many exis...
作者:Michael A. Lobritz , Annette N. Ratcliff , Eric J. Arts
来源:[J].Viruses(IF 2.509), 2010, Vol.2 (5), pp.1069DOAJ
摘要:Entry inhibitors represent a new class of antiretroviral agents for the treatment of infection with HIV-1. While resistance to other HIV drug classes has been well described, resistance to this new class is still ill defined despite considerable clinical use. Several potential me...
作者:Michael A. Lobritz , Annette N. Ratcliff , Eric J. Arts
来源:[J].Viruses(IF 2.509), 2010, Vol.2 (5), pp.1069-1105DOAJ
摘要:Entry inhibitors represent a new class of antiretroviral agents for the treatment of infection with HIV-1. While resistance to other HIV drug classes has been well described, resistance to this new class is still ill defined despite considerable clinical use. Several potential me...
作者:Michael A. Lobritz , Annette N. Ratcliff , Eric J. Arts
来源:[J].Viruses(IF 2.509), 2010, Vol.2 (5), pp.1069-1105CrossRef
作者:Michael A. Lobritz , Annette N. Ratcliff , Eric J. Arts
来源:[J].Viruses(IF 2.509), 2010, Vol.2 (5), pp.1069-1105MDPI
摘要:Entry inhibitors represent a new class of antiretroviral agents for the treatment of infection with HIV-1. While resistance to other HIV drug classes has been well described, resistance to this new class is still ill defined despite considerable clinical use. Several potential me...
作者:Annette N. Ratcliff , Jesse J. Kwiek
来源:[J].Cell Chemical Biology, 2016, Vol.23 (6), pp.678-688Elsevier
摘要:Summary(#br)Many tumors are dependent on de novo fatty acid synthesis to maintain cell growth. Fatty acid synthase (FASN) catalyzes the final synthetic step of this pathway, and its upregulation is correlated with tumor aggressiveness. The consequences and adaptive responses of a...

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