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作者:... Shaney L. Barratt , Gavin I. Welsh , Ann B. Millar
来源:[J].Respiratory Research(IF 3.642), 2017, Vol.18 (1)
摘要:Alternative splicing of Vascular endothelial growth factor-A mRNA transcripts (commonly referred as VEGF) leads to the generation of functionally differing isoforms, the relative amounts of which have potentially significant physiological outcomes in conditions such as acute resp...
作者:Ann B. Millar , Carol A. Feghali-Bostwick ...
来源:[J].The Journal of Allergy and Clinical Immunology(IF 12.047), 2016
摘要:Background(#br)Idiopathic pulmonary fibrosis (IPF) is progressive and rapidly fatal. Improved understanding of pathogenesis is required to prosper novel therapeutics. Epigenetic changes contribute to IPF; therefore, microRNAs may reveal novel pathogenic pathways.(#br)Objecti...
作者:... Leigh J. Keen , Jeffrey L. Bidwell , Ann B. Millar
来源:[J].Chest(IF 5.854), 2009, Vol.136 (2), pp.457-464
摘要:Background(#br)Vascular endothelial growth factor (VEGF) is postulated to have a role in ARDS. The functional VEGF + 936 polymorphic T allele is associated with an increased susceptibility to and severity of ARDS. The reasons for this are unclear. We hypothesized that the T ...
作者:Andrew R.L. Medford , Nassif B.N. Ibrahim , Ann B. Millar
来源:[J].Journal of Critical Care(IF 2.498), 2009, Vol.24 (2), pp.236-242
摘要:Abstract(#br)Background(#br)Acute respiratory distress syndrome (ARDS) is characterized by the development of noncardiogenic pulmonary edema, which has been related to the bioactivity of vascular endothelial growth factor (VEGF). Vascular endothelial growth factor receptors ...
作者:... Syed A. Husain , Hesham M. Turki , Ann B. Millar
来源:[J].Journal of Critical Care(IF 2.498), 2008, Vol.24 (3), pp.473.e1-473.e6
摘要:Abstract(#br)Introduction(#br)Ventilator-associated pneumonia (VAP) is difficult to diagnose. Recent data suggest quantitative endotracheal aspirate (ETA) may be noninferior diagnostically to quantitative bronchoalveolar lavage (BAL). We hypothesized this would be the case.(#br)M...
作者:Charles Sharp , Huzaifa I. Adamali , Ann B. Millar
来源:[J].ERJ Open Research, 2017, Vol.3 (1)
摘要:Idiopathic pulmonary fibrosis (IPF) has an unpredictable course and prognostic factors are incompletely understood. We aimed to identify prognostic factors, including multidimensional indices from a significant IPF cohort at the Bristol Interstitial Lung Disease Centre in the UK....
作者:... Victoria A. Flower , John D. Pauling , Ann B. Millar
来源:[J].International Journal of Molecular Sciences(IF 2.464), 2018, Vol.19 (5)
摘要:Interstitial lung disease (ILD) encompasses a group of heterogeneous diseases characterised by varying degrees of aberrant inflammation and fibrosis of the lung parenchyma. This may occur in isolation, such as in idiopathic pulmonary fibrosis (IPF) or as part of a wider disease p...
作者:Ann B. Millar , Andrew H. J. Salmon ...
来源:[J].PLOS ONE(IF 3.73), 2013, Vol.8 (7)
摘要:Vascular Endothelial Growth Factor-A (VEGF-A) can be generated as multiple isoforms by alternative splicing. Two families of isoforms have been described in humans, pro-angiogenic isoforms typified by VEGF-A165a, and anti-angiogenic isoforms typified by VEGF-A165<...
作者:Charles Sharp , Huzaifa I. Adamali , Ann B. Millar
来源:[J].ERJ Open Research, 2017, Vol.3 (1)
摘要:Idiopathic pulmonary fibrosis (IPF) has an unpredictable course and prognostic factors are incompletely understood. We aimed to identify prognostic factors, including multidimensional indices from a significant IPF cohort at the Bristol Interstitial Lung Disease Centre in the UK....

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