全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Andreoni Alessio , Banal James L ...
来源:[J].Nature materials(IF 35.749), 2017PubMed
摘要:Natural light-harvesting systems spatially organize densely packed chromophore aggregates using rigid protein scaffolds to achieve highly efficient, directed energy transfer. Here, we report a synthetic strategy using rigid DNA scaffolds to similarly program the spatial organizat...
作者:Andreoni Alessio , Cojocaru Razvan ...
来源:[J].Biochemistry, 2018PubMed
摘要:Several RNA aptamers that bind small molecules and enhance their fluorescence have been successfully used to tag and track RNAs in vivo, but these genetically encodable tags have not yet achieved single-fluorophore resolution. Recently, Mango-II, an RNA that binds TO1-Biotin with...
作者:Andreoni Alessio , Cojocaru Razvan ...
来源:[J].Nature chemical biology, 2019, Vol.15 (5), pp.472-479PubMed
摘要:Several turn-on RNA aptamers that activate small-molecule fluorophores have been selected in vitro. Among these, the ~30 nucleotide Mango-III is notable because it binds the thiazole orange derivative TO1-Biotin with high affinity and fluoresces brightly (quantum yield 0.55). Uni...
作者:Andreoni Alessio , Knutson Jay R ...
来源:[J].The Journal of physiology, 2019, Vol.597 (22), pp.5411-5428PubMed
摘要:KEY POINTS(#br)We developed a novel metabolic imaging approach that provides direct measures of the rate of mitochondrial energy conversion with single-cell and subcellular resolution by evaluating NADH autofluorescence kinetics during the mitochondrial redox after cyanide experi...
作者:Andreoni Alessio , Lin Su ...
来源:[J].Nano letters, 2017, Vol.17 (2), pp.1174-1180PubMed
摘要:Taking inspiration from photosynthetic mechanisms in natural systems, we introduced a light-sensitive photo protective quenching element to an artificial light-harvesting antenna model to control the flow of energy as a function of light intensity excitation. The orange carotenoi...
作者:Andreoni Alessio , Sen Saptaswa ...
来源:[J].Chemistry (Weinheim an der Bergstrasse, Germany), 2017PubMed
摘要:Fluorescent labeling of biomacromolecules enjoys increasing popularity for structural, mechanistic, and microscopic investigations. Its success hinges on the ability of the dye to alternate between bright and dark states. Förster resonance energy transfer (FRET) is an import...
作者:Andreoni Alessio , Cojocaru Razvan ...
来源:[J].Biochemistry, 2018, Vol.57 (26), pp.3544-3548PubMed
摘要:Several RNA aptamers that bind small molecules and enhance their fluorescence have been successfully used to tag and track RNAs in vivo, but these genetically encodable tags have not yet achieved single-fluorophore resolution. Recently, Mango-II, an RNA that binds TO1-Biotin...
作者:Andreoni Alessio , Rosales Tilman ...
来源:[J].Journal of biomedical optics, 2018, Vol.23 (10), pp.1-14PubMed
摘要:Oxygen (O2) is one of the most important biometabolites. In abundance, it serves as the limiting terminus of aerobic respiratory chains in the mitochondria of higher organisms; in deficit, it is a potent determinant of development and regulation of other physiological and therape...
作者:Andreoni Alessio , Cojocaru Razvan ...
来源:[J].Nature chemical biology, 2019, Vol.15 (5), pp.472-479PubMed
摘要:Several turn-on RNA aptamers that activate small-molecule fluorophores have been selected in vitro. Among these, the ~30 nucleotide Mango-III is notable because it binds the thiazole orange derivative TO1-Biotin with high affinity and fluoresces brightly (quantum yield 0.55). Uni...

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