全部文献期刊会议图书|学者科研项目
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作者:Alessandra Bitto , Daniela Giuliani ...
来源:[J].Inflammation Research(IF 1.964), 2017, Vol.66 (5), pp.389-398
摘要:Alzheimer’s disease (AD) is associated with amyloid plaques (Aβ) and hyperphosphorylated tau protein tangles in the brain. We investigated the possible neuroprotective role of flavocoxid, a dual inhibitor of cyclooxygenases-1/2 (COX-1/2) and 5-Lipoxygenase (5-LOX), in triple...
作者:Alessandra Bitto , Claudio Ferrante ...
来源:[J].Pharmacological Research(IF 4.346), 2020, Vol.152
摘要:Abstract(#br)The somatotropic axis, in addition to its well-known metabolic and endocrine effects, plays a pivotal role in modulation of inflammation. Moreover, growth hormone (GH)-releasing hormone (GHRH) has been involved in the development of various human tumors. In this...
作者:Alessandra Bitto , Federica Mannino ...
来源:[J].Bioorganic & Medicinal Chemistry Letters(IF 2.338), 2018, Vol.28 (3), pp.278-283
摘要:Abstract(#br)This paper describes the design, synthesis, and biological evaluation of 2-thioxoimidazolidin-4-one derivatives as inhibitors of proteasome and immunoproteasome, potential targets for the treatment of hematological malignancies. In particular, we focused our eff...
作者:Alessandra Bitto , Roberto Salvatori
来源:[J].Prostaglandins and Other Lipid Mediators(IF 2.422), 2019, Vol.144
摘要:Abstract(#br)Growth hormone (GH) and GH-releasing hormone (GHRH), in addition to metabolic and endocrine effects, play a role in the modulation of pain and inflammation. We aimed to elucidate the consequences of GHRH deficiency on acute nociceptive stimulation and on both ac...
作者:Alessandra Bitto , Fiorella Forte ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2017, Vol.132, pp.108-117
摘要:Abstract(#br)Aims(#br)Diabetic kidney disease (DKD) and retinopathy (DR) develop in a considerable number of subjects with Type 2 Diabetes (T2D) despite the achievement of the recommended targets for glycaemia and blood pressure. Atherogenic dyslipidemia may play a relevant ...
作者:Alessandra Bitto , Vincenzo Arcoraci ...
来源:[J].Endocrine(IF 2.25), 2017, Vol.55 (3), pp.899-906
摘要:Abstract(#br)During menopause, an increased prevalence of metabolic syndrome (MetS) and central obesity seems to increase hot flashes (HFs). Visfatin is an inflammatory adipokine secreted by visceral fat. We investigated visfatin levels and its relationship with hot flash number ...
作者:... Domenica Altavilla , Francesco Squadrito , Alessandra Bitto
来源:[J].Journal of Enzyme Inhibition and Medicinal Chemistry(IF 1.495), 2019, Vol.34 (1), pp.1307-1313
摘要:Proteasome inhibition is a promising strategy for the treatment of multiple myeloma; unfortunately, this disease is often associated with an increasing chemoresistance. One novel approach may be to target the immunoproteasome, a proteasomal isoform mainly present in cells of...
作者:Alessandra Bitto , Elena Bianca Adamo ...
来源:[J].Nutrients(IF 2.072), 2017, Vol.9 (6)
摘要:Genistein, a soy-derived isoflavone, may improve cardiovascular risk profile in postmenopausal women with metabolic syndrome (MetS), but few literature data on its cardiac effects in humans are available. The aim of this sub-study of a randomized double-blind case-control st...
作者:Alessandra Bitto , Giovanni Pallio ...
来源:[J].Oxidative Medicine and Cellular Longevity(IF 3.393), 2017, Vol.2017
摘要:Experimental evidence suggests that cadmium (Cd) boosts oxidative stress that may result in toxicity on the endocrine system also in humans. The aim of this study was to investigate the glycemic control and oxidative stress markers in male adolescents with increased urinary ...

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