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作者:Aleksandra Rutkowska , Andreas W. Sailer , Kumlesh K. Dev
来源:[J].Journal of Neuroinflammation(IF 4.351), 2017, Vol.14 (1)
摘要:The G protein-coupled receptor EBI2 (Epstein-Barr virus-induced gene 2) is activated by 7α, 25-dihydroxycholesterol (7α25HC) and plays a role in T cell-dependant antibody response and B cell migration. Abnormal EBI2 signaling is implicated in a range of autoimmune disorders;...
作者:Aleksandra Rutkowska , Derya R. Shimshek ...
来源:[J].Neuropharmacology(IF 4.114), 2018, Vol.133, pp.121-128
摘要:Abstract(#br)The endogenous oxysterol 7α, 25-dihydroxycholesterol (7α25HC) ligand activates the G protein-coupled receptor EBI2 to regulate T cell-dependant antibody response and B cell migration. We have demonstrated that EBI2 is expressed in human and mouse astrocytes, tha...
作者:Dariusz Walczak , Aleksandra Rutkowska
来源:[J].European Journal of Operational Research(IF 2.038), 2017, Vol.260 (2), pp.706-714
摘要:Abstract(#br)In this study, a fuzzy technique is proposed for order preference based on the similarity to an ideal solution for the personalized ranking of projects in a participatory budget (PB). A PB is a group decision-making process where citizens distribute public resou...
作者:Aleksandra Rutkowska , Aleksandra Konieczna ...
来源:[J].Science of the Total Environment(IF 3.258), 2018, Vol.628-629, pp.1362-1368
摘要:Abstract(#br)Chemicals showing structural or functional similarity to bisphenol A (BPA), commonly called BPA analogues, have recently drawn scientific attention due to their common industrial and commercial application as a substitute for BPA. In the European Union, the use ...
作者:Aleksandra Rutkowska , Marcin Gruchała ...
来源:[J].Cellular Immunology(IF 1.743), 2017, Vol.322, pp.26-33
摘要:Abstract(#br)Lung cancer cells harboring multiple mutations as a consequence of long-term damage by different etiologic factors are responsible for high immunogenicity. Immune checkpoint inhibitors significantly improve treatment results in non-small cell lung cancer (NSCLC)...
作者:Aleksandra Rutkowska , Sinead A. O’Sullivan ...
来源:[J].Scientific Reports(IF 2.927), 2016, Vol.6 (1), pp.524-527
摘要:Abstract(#br)EBI2 is a G protein-coupled receptor activated by oxysterol 7α, 25-dihydroxycholesterol (7α25HC) and regulates T cell-dependant antibody response and B cell migration. We recently found EBI2 is expressed in human astrocytes, regulates intracellular signalling an...
作者:Aleksandra Rutkowska , Łukasz Hak ...
来源:[J].Clinical Immunology(IF 3.771), 2008, Vol.130 (3), pp.355-364
摘要:Abstract(#br)We analyzed the relationship between the IVS1-397 T > C polymorphism of estrogen receptor α gene and inflammatory response of eighty postmenopausal women with an established coronary artery disease (CAD). We found that the IVS1 -397T allele carriers exhibited an...
作者:Aleksandra Rutkowska , Kumlesh K. Dev , Andreas W. Sailer
来源:[J].Current Drug Targets(IF 3.848), 2016, Vol.17 (16), pp.1851-1860
摘要:Oxysterols are pleiotropic messengers interacting with multiple receptorsystems. One of the cognate receptors for oxysterols is EBI2, a G protein-coupled receptorhighly expressed in the cells of the immune system. Here we discuss the receptor'srole in the adapted immunity and inf...

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