全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:... Xun Lan , Jonathan K. Pritchard , Aaron P. Turkewitz
来源:[J].G3: Genes, Genomes, Genetics(IF 1.794), 2016, Vol.6 (8), pp.2505-2516DOAJ
摘要:Unbiased genetic approaches have a unique ability to identify novel genes associated with specific biological pathways. Thanks to next generation sequencing, forward genetic strategies can be expanded to a wider range of model organisms. The formation of secretory granules, ...
作者:Aaron P. Turkewitz , Mark C. Field
来源:[J].Molecular & Biochemical Parasitology(IF 2.734), 2016, Vol.209 (1-2), pp.88-103Elsevier
摘要:Abstract(#br)With advances in DNA sequencing technology, it is increasingly common and tractable to informatically look for genes of interest in the genomic databases of parasitic organisms and infer cellular states. Assignment of a putative gene function based on homology to fun...
作者:Aaron P. Turkewitz , Ana Martín-González
来源:[J].BioMetals(IF 3.284), 2014, Vol.27 (1), pp.195-205Springer
摘要:Abstract(#br)The significance of metal(oid)s as environmental pollutants has made them a priority in ecotoxicology, with the aim of minimizing exposure to animals or humans. Therefore, it is necessary to develop sensitive and inexpensive methods that can efficiently detect a...
作者:Aaron P. Turkewitz , Clara B. Nudel
来源:[J].Steroids(IF 2.803), 2012, Vol.77 (13), pp.1313-1320Elsevier
摘要:Abstract(#br)Tetrahymena thermophila is a free-living ciliate with no exogenous sterol requirement. However, it can perform several modifications on externally added sterols including desaturation at C5(6), C7(8), and C22(23). Sterol desaturases in Tetrahymena are microsomal...
作者:Alejandro D. Nusblat , Lydia J. Bright , Aaron P. Turkewitz
来源:[J].Methods in Cell Biology(IF 1.444), 2012, Vol.109, pp.141-175Elsevier
摘要:Abstract(#br)The past decade has seen a significant expansion in our understanding of membrane traffic in Tetrahymena thermophila , facilitated by the development of new experimental tools and by the availability of the macronuclear genome sequence. Here we review studies on mult...
作者:... Elisabeth Richardson , Joel B. Dacks , Aaron P. Turkewitz
来源:[J].Traffic(IF 4.652), 2017, Vol.18 (1), pp.18-28Wiley
摘要:As most of eukaryotic diversity lies in single‐celled protists, they represent unique opportunities to ask questions about the balance of conservation and innovation in cell biological features. Among free‐living protists the ciliates offer ease of culturing, a rich array of...
作者:Aaron P. Turkewitz , Eduardo Orias , Geoffrey Kapler
来源:[J].Trends in Genetics(IF 9.772), 2002, Vol.18 (1), pp.35-40Elsevier
摘要:Abstract(#br)Over the past decade, researchers have manipulated the unique biology of Tetrahymena thermophila to generate a premier experimental organism for functional genomic analysis. A diverse array of DNA transformation methods have spearheaded in vivo strategies for di...
作者:Aaron P. Turkewitz , N. Doane Chilcoat ...
来源:[J].Methods in Cell Biology(IF 1.444), 1999, Vol.62, pp.347-362Elsevier
摘要:Publisher Summary(#br)The genetic and molecular genetic accessibility of Tetrahymena makes possible a wide set of approaches that are unavailable in mammalian cells. The classical pathway for protein secretion begins with translocation of newly synthesized proteins across the end...

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