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作者:Cédric Bories , Robert Faure
来源:[J].Synthesis(IF 2.5), 2005, Vol.2005 (13), pp.2151-2156Thieme
摘要:A versatile and operationally simple base-catalyzed multi-component domino reaction between α,β-unsaturated carbonyl compounds, aldehydes, and alcohols is described, providing a new efficient, and stereoselective one-pot preparation of trisubstituted alkenes and 1,3-dienes.
作者:Cédric Bories , Bénédicte Fauvel ...
来源:[J].Med. Chem. Commun., 2012, Vol.3, pp.788-800RSC
摘要:A new fragment based drug design approach implemented in our MedChem-Decision platform led to the discovery of a new series of 2,5 disubstituted 7-azaindole derivatives as potent dual Abl and Src kinase inhibitors.

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