全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
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作者:Vera Y. Chung , Benjamin W. Turney
来源:[J].BMC Urology(IF 1.694), 2017, Vol.17 (1)Springer
摘要:... We have used Drosophila as a genetic model to study the transcriptional response to stone formation secondary to dietary manipulation.
作者:Damgaard Lars , Korsgaard Inge
来源:[J].Genetics Selection Evolution(IF 2.859), 2006, Vol.38 (6), pp.565DOAJ
摘要:... In this paper we derive and implement a bivariate quantitative genetic model for a threshold character and a survival trait that are genetically and environmentally correlated. For the survival trait, we considered the Weibull log-normal animal frailty model. A Bayesian appro...
作者:Ji Fei , Finch Stephen , Haynes Chad ...
来源:[J].BMC Genomics(IF 4.397), 2007, Vol.8 (1), pp.238DOAJ
摘要:... We use the non-centrality parameter (NCP) for the analysis of variance test to compute the approximate power for genetic association tests with DNA pooling data on cases and controls. We incorporate genetic model parameters into the computation of the NCP. Parameters involved...
作者:Shuo Sun , ZhiQing Li , Patrick Glencer ...
来源:[J].Stem Cell Research & Therapy(IF 3.652), 2017, Vol.8 (1)Springer
摘要:... It is a multifactorial disease triggered by both environmental and genetic factors. High-temperature requirement A serine peptidase 1 ( HTRA1 ) and age-related maculopathy susceptibility 2 ( ARMS2 ) are two genes that are strongly associated with AMD. Because ARMS2 is an ev...
作者:Tom J. de Jong
来源:[J].Journal of Consumer Protection and Food Safety(IF 0.667), 2017, Vol.12 (4), pp.299-307Springer
摘要:... I revisit the population genetic models of GD with the aim of making these models more understandable to non-specialists. What can we learn about risk evaluation from the models? A GD with no or a small effect on fitness (viability) always spreads in the population and goes t...
作者:Gang Zheng , Wei Zhang , Jinfeng Xu ...
来源:[J].Journal of Theoretical Biology(IF 2.351), 2016, Vol.403, pp.68-74Elsevier
摘要:Abstract(#br)Genetic risks and genetic models are often used in design and analysis of genetic epidemiology studies. A genetic model is defined in terms of two genetic risk measures: genotype relative risk and odds ratio. The impacts of choosing a risk measure on the resulting genetic models...
作者:Lide Han , Jian Yang , Jun Zhu
来源:[J].Journal of Genetics and Genomics(IF 2.076), 2007, Vol.34 (6), pp.562-568Elsevier
摘要:Abstract(#br)A genetic model was proposed for simultaneously analyzing genetic effects of nuclear, cytoplasm, and nuclear-cytoplasmic interaction (NCI) as well as their genotype by environment ( GE ) interaction for quantitative traits of diploid plants. In the model, the NCI eff...
作者:Gang Zheng , Wei Zhang , Qizhai Li ...
来源:[J].Journal of Agricultural, Biological, and Environmental Statistics(IF 1.235), 2015, Vol.20 (2), pp.173-191Springer
摘要:Abstract(#br)In genetic association studies, for each underlying genetic model, there is an optimal test. Usually, the true model is unknown, but knowledge from previous genome-wide association studies for the disease under investigation is available and provides information abo...
作者:Amadou Gaye , Sharon K. Davis
来源:[J].BMC Research Notes, 2017, Vol.10 (1)Springer
摘要:The underlying model of the genetic determinant of a trait is generally not known with certainty a priori. Hence, in genetic association studies, a dominant model might be erroneously modelled as additive, an error investigated previously. We explored this question, for candid...
作者:Petroula Proitsi , Michelle K. Lupton , Frank Dudbridge ...
来源:[J].Neurobiology of Aging(IF 6.166), 2012, Vol.33 (8), pp.1843.e9-1843.e17Elsevier
摘要:... The aim of this study was to investigate whether there is an association between well replicated AMD genetic risk factors and AD. A large cohort of AD ( n = 3898) patients and controls were genotyped for single nucleotide polymorphisms (SNPs) in the complement factor H (CFH),...

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