全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Hamoud Al-Khallaf
来源:[J].Cell & Bioscience(IF 3), 2017, Vol.7 (1)Springer
摘要:... A model explaining two important features of isocitrate dehydrogenases 1 and 2 mutations, their dominant negative effect and their mutual exclusivity, will be provided. The importance of targeting these mutations and the possibility of augmenting such therapy by targeting oth...
作者:Sriganesh Srihari , Jitin Singla , Limsoon Wong ...
来源:[J].Biology Direct(IF 2.72), 2015, Vol.10 (1)Springer
摘要:...(#br) Conclusion(#br)Mutual exclusivity between frequently occurring genetic events identifies synthetic lethal combinations in cancers. These identified genes are essential in cell lines, and are potential candidates for targeted cancer therapy. Availability: http://bioinform...
作者:S. A. van Dellen , B. Wisse , M. P. Mobach ...
来源:[J].BMC Public Health(IF 2.076), 2019, Vol.19 (1), pp.1-12DOAJ
摘要:... This study examined whether a comprehensive, evidence-based breastfeeding intervention, the Breastfeeding Support Programme (BSP), promotes prolonged duration and exclusivity of breastfeeding among its participants. Methods A quasi-experimental design was used to compare br...
作者:Lisa Diependaele , Julian Cockbain , Sigrid Sterckx
来源:[J].Developing World Bioethics(IF 0.833), 2017, Vol.17 (1), pp.11-21Wiley
摘要:... In addition to the market exclusivity provided by patents, the pharmaceutical industry has also sought to further extend their monopolies by advocating the need for additional ‘regulatory’ protection for new medicines, known as data exclusivity.(#br)Data exclusivity limi...
作者:Tim K Mackey , Bryan A Liang
来源:[J].PLoS ONE(IF 3.73), 2017, Vol.7 (11)DOAJ
摘要:... METHODS: Using the data sources listed below, the study design systematically eliminated NCD drugs that had no patent/exclusivity provisions on API, dosage, or administration route. The first step identified essential medicines that treat certain high disease burden NCDs. A s...
作者:Hao Wu , Lin Gao , Feng Li ...
来源:[J].BMC Bioinformatics(IF 3.024), 2015, Vol.16 (S5)Springer
摘要:... This algorithm can directly find driver pathways or gene sets de novo from somatic mutation data utilizing two combinatorial properties, high coverage and high exclusivity, without any prior information. We firstly construct gene networks based on the approximate exclusivity ...
作者:Ewa Szczurek , Niko Beerenwinkel
来源:[J].PLoS Computational Biology(IF 5.215), 2014, Vol.10 (3)DOAJ
摘要:..., additional alterations that violate strict mutual exclusivity. However, the extant approaches do not account for possible observation errors. In practice, false negatives and especially false positives can severely bias evaluation and ranking of alteration patterns. To addre...
作者:Tina W. Wey , Ann T. Chang , Sean Fogarty ...
来源:[J].Behavioral Ecology and Sociobiology(IF 2.752), 2015, Vol.69 (1), pp.27-37Springer
摘要:Abstract(#br)Male expected reproductive success can be enhanced by increased mating success (mate number) or, when females can mate multiply, by increased mating exclusivity (i.e., reduced partner promiscuity). A positive or negative covariance between these two mating outcomes...
作者:Ka Chun Cheung , Ambrose Lo
来源:[J].Insurance Mathematics and Economics(IF 1.095), 2014, Vol.55, pp.180-190Elsevier
摘要:Abstract(#br)Mutual exclusivity is an extreme negative dependence structure that was first proposed and studied in Dhaene and Denuit (1999) in the context of insurance risks. In this article, we revisit this notion and present versatile characterizations of mutually exclusive ran...
作者:Candace L. Rouse
来源:[J].Journal of Obstetric, Gynecologic & Neonatal Nursing(IF 1.033), 2015, Vol.44, pp.S49-S49Elsevier
摘要:Poster Presentation(#br)Objective(#br)To increase initiation and exclusivity of breastfeeding in the hospitalized, postpartum dyad via an educational module for staff registered nurses (RNs). This module consisted of interventions to increase bedside lactation support and bui...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×