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作者:Nikola Gligorijević , Tamara Vasović , Steva Lević ...
来源:[J].International Journal of Biological Macromolecules(IF 2.596), 2020
摘要:Abstract(#br)Clozapine is an atypical antipsychotic used for the treatment of schizophrenia. The prescribed target daily doses may reach 900 mg. Literature studies report a connection between clozapine usage and thrombosis development. Our in vitro study aimed to provide insi...
作者:Andre Delgado , Jorge Velosa , Junyu Zhang ...
来源:[J].Journal of Psychiatric Research(IF 4.066), 2020, Vol.125, pp.21-27
摘要:Abstract(#br)Objectives(#br)To assess the clinical efficacy of clozapine in bipolar disorder and its adverse effect profile.(#br)Methods(#br)A literature search with no year and no language restriction was conducted. The search yielded 3858 articles, with 2453 remaining after dup...
作者:Hélène Verdoux , Clélia Quiles , Christian J. Bachmann ...
来源:[J].Schizophrenia Research(IF 4.59), 2018
摘要:Abstract(#br)Background(#br)As clozapine is under-prescribed in persons with treatment-resistant schizophrenia (TRS), it is necessary to better identify the determinants of health inequalities in access to clozapine use.(#br)Objective(#br)To identify mental health professionals' ...
作者:Francesco Dal Santo , Isaac Jarratt-Barnham , Leticia González-Blanco ...
来源:[J].European Neuropsychopharmacology(IF 4.595), 2020
摘要:Abstract(#br)Previous cross-sectional studies have found clozapine to N -desmethylclozapine (CLZ:NDMC) ratio to be negatively correlated with cognition in clozapine-treated patients with schizophrenia. However, no work has examined the association between CLZ:NDMC ratio and cogni...
作者:Rajendra P. Shukla , Remi Cazelles , Deanna L. Kelly ...
来源:[J].Talanta(IF 3.498), 2020, Vol.209
摘要:Abstract(#br)Antipsychotic clozapine is the most effective medication currently available for schizophrenia. However, clozapine is dramatically underutilized due to its harsh side effects that are not effectively monitored. By continuously monitoring clozapine blood levels, ...
作者:Hélène Verdoux , Clélia Quiles , Jose de Leon
来源:[J].Schizophrenia Research(IF 4.59), 2019, Vol.211, pp.1-9
摘要:Abstract(#br)Objectives(#br)To identify the clinical determinants of fever in clozapine users and their impact on management of clozapine treatment.(#br)Methods(#br)Articles published in English or French identified with a MEDLINE, Web of Sciences, Cochrane Library and PsycINF...
作者:Stephen West , David Rowbotham , Glen Xiong ...
来源:[J].General Hospital Psychiatry(IF 2.977), 2017
摘要:Abstract(#br)Objective(#br)The haematological and cardiac complications of clozapine have been well documented. Recent evidence from pharmacovigilance databases suggests that gastrointestinal (GI) complications are the leading cause of clozapine related deaths. This review aims t...
作者:Essam Daod , Amir Krivoy , Gal Shoval ...
来源:[J].Psychiatry Research(IF 2.456), 2019, Vol.275, pp.155-161
摘要:Abstract(#br)Objectives(#br)Clozapine is the most effective treatment for refractory schizophrenia, yet it remains underused in clinical practice. The current study examined the awareness, familiarity and attitude of a nationwide sample of Israeli psychiatrists regarding the use ...
作者:Belén Arranz , Marina Garriga , Clemente García-Rizo ...
来源:[J].European Neuropsychopharmacology(IF 4.595), 2018, Vol.28 (2), pp.227-242
摘要:... Amongst antipsychotics, clozapine shows positive evidence in the literature. The aim of the present article is to provide systematic review on the efficacy of clozapine in SUD improvement in schizophrenic patients. PRISMA recommendations were followed (PROSPERO id: CRD4201...
作者:J.W.Y. Yuen , C. Wu , C.K. Wang ...
来源:[J].Neuropharmacology(IF 4.114), 2019
摘要:Abstract(#br)Rationale(#br)The second generation antipsychotic drug clozapine is a psychotherapeutic agent with superior efficacy for treatment-resistant schizophrenia. Clozapine is associated with a low likelihood of neurological side-effects, but a high propensity to induce w...

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