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作者:Aschalew Tamiru , Bethlehem Tigabu , Sisay Yifru ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2016, Vol.16 (1)Springer
摘要:... The mainstay of treatment in resource limited countries like Ethiopia is antimonials, while use of liposomal amphotericin B is reserved for treatment of complicated VL cases. The aim of this study was to assess the safety and efficacy of liposomal amphotericin B in HIV ne...
作者:Ruwandi Kariyawasam , Priyanka Challa , Rachel Lau ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2019, Vol.19 (1), pp.1-9DOAJ
摘要:Abstract Background Current drug regimens for cutaneous leishmaniasis (CL) include toxic systemic therapies such as amphotericin B (AB) and pentavalent antimonials. Fluconazole (FZ) is a well-tolerated potential oral alternative for the management CL. To date, few objective ...
作者:Anna Eichenberger , Annina E. Buechi , Andreas Neumayr ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2017, Vol.17 (1)Springer
摘要:... This case is furthermore unusual because it suggests primary treatment failure to liposomal amphotericin B.
作者:Mohammad Asad , Pradyot Bhattacharya , Antara Banerjee ...
来源:[J].BMC Infectious Diseases(IF 3.025), 2015, Vol.15 (1)Springer
摘要:... Since the conventional antileishmanial drugs have many limitations we evaluated a new ergosterol rich liposomal amphotericin B formulation, KALSOME™10 for its leishmanicidal efficacy, tolerability and immunomodulatory activity.(#br) Methods(#br)Normal healthy mice were t...
作者:Azmat Ali Khan , Mumtaz Jabeen , Amer M Alanazi ...
来源:[J].Brazilian Journal of Infectious Diseases(IF 1.036), 2016, Vol.20 (4), pp.342-348Elsevier
摘要:... In the present study, we evaluated the systemic augmentation of the antifungal activity of amphotericin B loaded in fibrin microsphere (AMB-fibrin microsphere) against cryptococcosis in Swiss albino mice. Mice infected with Cryptococcus neoformans were treated with 0.5 mg/kg ...
作者:Yuka Ohata , Yoshiko Tomita , Kota Suzuki ...
来源:[J].Drug Metabolism and Pharmacokinetics(IF 2.071), 2015, Vol.30 (6), pp.400-409Elsevier
摘要:Abstract(#br)The pharmacokinetic characteristics of liposomal amphotericin B (L-AMB; AmBisome ® ) in patients with invasive fungal infection were investigated. A population pharmacokinetic (PK) model in Japanese pediatric patients was developed based on 159 serum amphotericin B...
作者:Joanna Gola , Barbara Strzałka-Mrozik , Celina Kruszniewska-Rajs ...
来源:[J].Pharmacological Reports(IF 1.965), 2017, Vol.69 (1), pp.22-28Elsevier
摘要:Abstract(#br)Background(#br)A new form of amphotericin B (AmB)– complex with copper (II) ions (AmB–Cu 2+ ) – is less toxic to human renal cells. Cytokines, including Tumor Necrosis Factor (TNF), are responsible for nephrotoxicity observed in patients treated with AmB. An...
作者:Jadhav M , Bamba A , Shinde V ...
来源:[J].Journal of Postgraduate Medicine(IF 1.263), 2010, Vol.56 (2), pp.71DOAJ
摘要:Background : There is need to investigate the use of liposomal amphotericin B in cryptococcal meningitis in India. Aims : To compare the efficacy, safety, duration of treatment and cost of two doses of liposomal amphotericin B (Amp B) (Fungisome TM ) in cryptococcal ...
作者:Mohamed El-Azizi , Noha Farag , Nancy Khardori
来源:[J].Annals of Clinical Microbiology and Antimicrobials(IF 1.623), 2015, Vol.14 (1)Springer
摘要:... The aim of the study is to evaluate the activity of amphotericin B and voriconazole against the biofilm and the biofilm-dispersed cells of Candida albicans using a newly developed in vitro pharmacokinetic model which simulates the clinical situation when the antifungal a...
作者:Azmat Ali Khan , Mumtaz Jabeen , Amer M Alanazi ...
来源:[J].Brazilian Journal of Infectious Diseases(IF 1.036), 2016, Vol.20 (4), pp.342-348DOAJ
摘要:... In the present study, we evaluated the systemic augmentation of the antifungal activity of amphotericin B loaded in fibrin microsphere (AMB-fibrin microsphere) against cryptococcosis in Swiss albino mice. Mice infected with Cryptococcus neoformans were treated with 0.5 mg/kg ...

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