全部文献期刊学位论文会议报纸专利标准年鉴图书|学者科研项目
中外文文献  中文文献  外文文献
作者:Maddalena Barba , Patrizia Vici , Laura Pizzuti ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Body mass index (BMI) is largely investigated as a prognostic and predictive factor in triple-negative breast cancer (TNBC). Overweight and obesity are linked to a variety of pathways regulating tumor-promoting functions, including the DNA damage response (DDR). The DDR physiolog...
作者:Jie Li , Yuanhui Lai , Jieyi Ma ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Triple-negative breast cancer (TNBC) is the malignancy with the worst outcome among all breast cancer subtypes. We reported that ETV1 is a significant oncogene in TNBC tumourigenesis. Consequently, investigating the critical regulatory microRNAs (miRNAs) of ETV1 may be beneficial...
作者:Melissa Quintero , Douglas Adamoski , Larissa Menezes dos Reis ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Triple-negative breast cancer (TNBC) is characterized by a lack of estrogen and progesterone receptor expression ( ESR and PGR , respectively) and an absence of human epithelial growth factor receptor ( ERBB2 ) amplification. Approximately 15–20% of breast malignancies are TN...
作者:Kerri-Ann Norton , Travis Wallace , Niranjan B. Pandey ...
来源:[J].BMC Systems Biology(IF 2.982), 2017, Vol.11 (1)Springer
摘要:Triple-negative breast cancer lacks estrogen, progesterone, and HER2 receptors and is thus not possible to treat with targeted therapies for these receptors. Therefore, a greater understanding of triple-negative breast cancer is necessary for the treatment of this cancer type. In...
作者:Susanne Schüler-Toprak , Julia Häring , Elisabeth C. Inwald ...
来源:[J].BMC Cancer(IF 3.333), 2016, Vol.16 (1)Springer
摘要:Abstract(#br) Background(#br)Estrogen receptor β (ERβ) is expressed in the majority of invasive breast cancer cases, irrespective of their subtype, including triple-negative breast cancer (TNBC). Thus, ERβ might be a potential target for therapy of this challenging cancer...
作者:Shang-Pen Huang , Pei-Yao Liu , Chih-Jung Kuo ...
来源:[J].Journal of Hematology & Oncology(IF 4.458), 2017, Vol.10 (1)Springer
摘要:Distant metastasis of triple-negative breast cancer (TNBC) to other organs, e.g., the lungs, has been correlated with poor survival rates among breast cancer patients. Therefore, the identification of useful therapeutic targets to prevent metastasis or even inhibit tumor growt...
作者:Wei Song , Lin Tang , Yumei Xu ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:Increasing evidence has indicated an important role for estrogen receptor beta 1 (ERβ1) in breast cancer. However, the role of ERβ1 in the metastasis of androgen receptor (AR)-positive triple-negative breast cancer (TNBC) and the underlying mechanisms are still unknown.
作者:Bo Chen , Jin Wang , Danian Dai ...
来源:[J].Journal of Experimental & Clinical Cancer Research(IF 3.066), 2017, Vol.36 (1)Springer
摘要:AHNAK, also known as desmoyokin, is a giant protein with the molecular size of approximately 700 kDa and exerts diverse functions in different types of cancer.
作者:Yuji Yamashita , Shin Nishiumi , Seishi Kono ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Triple-negative breast cancer (TN) is more aggressive than other subtypes of breast cancer and has a lower survival rate. Furthermore, detailed biological information about the disease is lacking. This study investigated characteristics of metabolic pathways in TN.
作者:Qian Wang , Yu Cheng , Yan Wang ...
来源:[J].BMC Cancer(IF 3.333), 2017, Vol.17 (1)Springer
摘要:Although the efficacy of tamoxifen (TAM) for breast cancer has been attributed to inducing cell cycle arrest and apoptosis by inhibiting estrogen receptor (ER) signaling, recent evidence indicates that TAM also possesses ER-independent antitumor activity through an unclear mechan...

我们正在为您处理中,这可能需要一些时间,请稍等。

资源合作:cnki.scholar@cnki.net, +86-10-82896619   意见反馈:scholar@cnki.net

×