全部文献期刊会议图书|学者科研项目
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作者:Tomohiro Yoshida , Shingo Yamasaki , Osamu Kaneko ...
来源:[J].Biochemical and Biophysical Research Communications(IF 2.406), 2020, Vol.522 (3), pp.633-638Elsevier
摘要:... Among these, recent studies have demonstrated that glutamate-oxaloacetate transaminase 1 (GOT1) plays key roles in maintaining redox homeostasis and proliferation of pancreatic ductal adenocarcinomas (PDA). This suggests that small molecule inhibitors of GOT1 could have ...
作者:Chang Ho Ahn , Jin-Young Jang , Seong Ok Lee ...
来源:[J].Diabetes Research and Clinical Practice(IF 2.741), 2018, Vol.143, pp.232-238Elsevier
摘要:Abstract(#br)Aims(#br)To investigate the changes of post-procedural liver transaminase levels after autologous islet transplantation (ITx), and their associations with glycemic outcomes.(#br)Methods(#br)Non-diabetic patients who underwent distal pancreatectomy for benign tumo...
作者:Shuaihua Gao , Yu Su , Lu Zhao ...
来源:[J].Process Biochemistry(IF 2.414), 2017, Vol.63, pp.130-136Elsevier
摘要:... In this study, a new ( R )-enantioselective amine transaminase from Fusarium oxysporum (ATFo) was identified by genome mining. ATFo possibly evolved from a branched chain amino acid aminotransferase (BCAT) with key amino acids being changed, which belong to one of the thr...
作者:Li-Qun Jin , Feng Peng , Han-Lin Liu ...
来源:[J].Process Biochemistry(IF 2.414), 2019, Vol.85, pp.60-67Elsevier
摘要:... Asymmetric synthesis of L-PPT from 4-(hydroxy(methyl)phosphoryl)-2-oxobutanoic acid (PPO) using transaminase is of great significance due to the 100% theoretical yield and high enantioselectivity. In this study, a new transaminase from Pseudomonas fluorescens ZJB09-108 (name...
作者:Krista M. Dale , C. Michael White , Nickole N. Henyan ...
来源:[J].The American Journal of Medicine(IF 4.768), 2006, Vol.120 (8), pp.706-712Elsevier
摘要:...(#br)Results(#br)Higher intensity statin therapy increased the incidence of transaminase elevations (RR 3.10 [95% Confidence Interval [CI], 0.88-7.85]) versus lower intensity statin therapy. When studies of hydrophilic and lipophilic statins were evaluated separately, high...
作者:Feng Shi , Han Si , Yalan Ni ...
来源:[J].Process Biochemistry(IF 2.414), 2017, Vol.55, pp.55-60Elsevier
摘要:... GABA is decomposed to succinic semialdehyde (SSA) by GABA transaminase (GABA-T) and to succinate thereafter by SSA dehydrogenase (SSADH). However, deletion of the gabT gene encoding GABA-T could not prevent GABA from decomposing at neutral pH. In this study, an additional transaminase...
作者:Dong-Fang Xie , Jun-Xing Yang , Chang-Jiang Lv ...
来源:[J].Journal of Biotechnology(IF 3.183), 2019Elsevier
摘要:... In this study, stabilized variants of the ( R )-selective amine transaminase from Aspergillus terreus (AT-ATA) were constructed by consensus mutagenesis. Using Consensus Finder ( http://cbs-kazlab.oit.umn.edu/ ), six positions with the most prevalent amino acid (over 60%...
作者:Guo-Ping Wang , Ginny T. T. Lim , David A. Jones
来源:[J].Molecular Breeding(IF 3.251), 2007, Vol.19 (3), pp.209-214Springer
摘要:... Based on their bin locations, these markers are largely dispersed throughout the tomato genome and appear to have tagged all four of the glutamate oxaloacetate transaminase (Got ) isozyme marker genes placed on the classical genetic map of tomato. Orthologous relationships wi...
作者:Lorenzo Cerioli , Matteo Planchestainer , Jennifer Cassidy ...
来源:[J].Journal of Molecular Catalysis. B, Enzymatic(IF 2.823), 2015, Vol.120, pp.141-150Elsevier
摘要:... HEWT is a novel amine transaminase from the moderate halophilic bacterium, Halomonas elongata DSM 2581, which is highly ( S )-selective, being able to fully convert ( S )-1-phenylethylamine to acetophenone and showing no activity with the corresponding ( R )-1-phenylethylam...
作者:Kenneth W. Ellens , Lynn G.L. Richardson , Océane Frelin ...
来源:[J].Phytochemistry(IF 3.05), 2015, Vol.113, pp.160-169Elsevier
摘要:... In mammals, glutamine transaminase K (GTK) and ω-amidase (ω-Am) are thought to act in tandem to execute this step, with GTK forming α-ketoglutaramate, which ω-Am hydrolyzes. Comparative genomics indicated that GTK and ω-Am could function likewise in plants and bacteria...

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